Bryant G H, Cucinell S A, Barcia P J
J Surg Res. 1985 Sep;39(3):224-9. doi: 10.1016/0022-4804(85)90146-5.
The measurement of blood flow in the inferior vena cava (IVC) by thermodilution may be useful in the determination of hepatic venous blood flow (HVBF), but is subject to major errors. The most serious error is gain of heat from the abdominal viscera by the cool thermodiluent bolus as it moves up the IVC. The determination or elimination of this heat gain is necessary for accurate IVC blood flow measurement. By comparison of the area under the curve (AUC) for cardiac output following femoral vein injection of the thermodiluent bolus to the AUC following right ventricular injection of the thermodiluent, it is possible to quantitatively determine the unidirectional heat gain by the bolus at it moves up the IVC. The heat gain varied from 0 to 40% of the thermodiluent injected. The factors that aggravated the heat gain were a low cardiac output (below 4000 ml/mn), a large thermodiluent calorie load (over -40 calories), and possibly a slow transit time. The error due to heat gain may be effectively eliminated by keeping the size of the thermodiluent bolus below 40 negative calories.
通过热稀释法测量下腔静脉（IVC）血流可能有助于确定肝静脉血流（HVBF），但存在较大误差。最严重的误差是冷的热稀释剂团块在IVC中向上移动时从腹部内脏获得热量。准确测量IVC血流需要确定或消除这种热量获取。通过比较股静脉注射热稀释剂团块后心输出量的曲线下面积（AUC）与右心室注射热稀释剂后的AUC，可以定量确定团块在IVC中向上移动时的单向热量获取。热量获取量占注入热稀释剂的0%至40%不等。加剧热量获取的因素包括低心输出量（低于4000毫升/分钟）、大热稀释剂热量负荷（超过-40卡路里），以及可能的缓慢传输时间。通过将热稀释剂团块的大小保持在低于40负卡路里，可以有效消除因热量获取导致的误差。
