Suciu D
J Theor Biol. 1985 Apr 21;113(4):599-609. doi: 10.1016/s0022-5193(85)80182-x.
The radiosensitive cell populations, such as resting lymphocytes from thymus, spleen, lymph node and blood, have much smaller nuclei (Vn (nuclear volume) approximately 20 to 70 microns3) compared to radioresistant G0 cells from non-lymphoid tissues (liver, kidney, brain, heart; Vn approximately 75 to 2700 microns3). It is suggested that radiation-induced disorganization of nuclear structures and cell pycnosis (interphase death) are promoted in G0 lymphocytes because in normal physiological conditions their nuclei assume a higher degree of chromatin condensation. In contrast, dispersion of chromatin into larger nuclear volumes, such as those of most non-lymphoid G0 cells, may hinder or delay radiation-induced cell death.
与来自非淋巴组织（肝脏、肾脏、大脑、心脏；核体积约75至2700立方微米）的抗辐射G0细胞相比，诸如来自胸腺、脾脏、淋巴结和血液的静止淋巴细胞等放射敏感细胞群体的细胞核要小得多（核体积约20至70立方微米）。有人提出，辐射诱导的核结构紊乱和细胞固缩（间期死亡）在G0淋巴细胞中更为常见，因为在正常生理条件下，它们的细胞核具有更高程度的染色质凝聚。相比之下，染色质分散到更大的核体积中，比如大多数非淋巴G0细胞的核体积，可能会阻碍或延迟辐射诱导的细胞死亡。
