Suciu D
Int J Radiat Biol Relat Stud Phys Chem Med. 1981 Jun;39(6):641-7. doi: 10.1080/09553008114550761.
The radioresistant tissues, heart, liver, lung and kidney, contain 2 to 15 times more protein per cell, nucleus and chromatin compared with the radiosensitive tissues, spleen and thymus. As determined by polyacrylamide gel electrophoresis, in the nuclear fraction and chromatin of radiosensitive tissues there is a deficit of high molecular weight (Mw greater than 20 000) non-histone proteins. It is suggested that the radiosensitivity of lymphoid cells, which die of interphase death a few hours after exposure to small doses of radiation, is closely correlated with this deficit in non-histone proteins.
抗辐射组织，如心脏、肝脏、肺和肾脏，与辐射敏感组织，如脾脏和胸腺相比，每个细胞、细胞核和染色质中的蛋白质含量多2至15倍。通过聚丙烯酰胺凝胶电泳测定，在辐射敏感组织的细胞核部分和染色质中，高分子量（分子量大于20000）非组蛋白存在不足。有人认为，淋巴样细胞在受到小剂量辐射后几小时就死于间期死亡，其辐射敏感性与这种非组蛋白的不足密切相关。
