全胰切除术后胰岛自体移植后的腹痛
Abdominal Pain Following Total Pancreatectomy With Islet Autotransplantation.
作者信息
Harrison Julia, Shaaban Mohamed A, Scheidecker Emily, Ramanathan Karthik, Freeman Martin, Trikudanathan Guru, Martin David, Chinnakotla Srinath, Downs Elissa M, Schwarzenberg Sarah Jane, Bellin Melena D, Beilman Greg
机构信息
University of Minnesota.
出版信息
Pancreas. 2025 Sep 1;54(8):e719-e727. doi: 10.1097/MPA.0000000000002510.
OBJECTIVE
Total pancreatectomy with islet autotransplantation (TPIAT) is increasingly used as an option for the treatment of chronic and recurrent acute pancreatitis in selected patients. Studies have shown significant improvements in pain, quality of life, and opioid use postoperatively. However, in long-term follow-up, over half of the patients have episodes of abdominal pain following TPIAT. The aim of this work is to describe the array of causes of abdominal pain in this complex and growing patient population.
METHODS
We conducted multidisciplinary discussions with experts at our institution and reviewed literature, where available, to identify and describe the diverse causes of abdominal pain following TPIAT.
RESULTS
We identify 15 distinct causes of abdominal pain following TPIAT, describing their presentation, workup, and management.
CONCLUSION
As more patients undergo TPIAT, we must plan for and address the associated causes of abdominal pain that result from alterations in anatomy and physiology, both in the short and long term.
目的
全胰切除联合胰岛自体移植术（TPIAT）越来越多地被用作特定患者慢性和复发性急性胰腺炎的治疗选择。研究表明，术后疼痛、生活质量和阿片类药物使用情况有显著改善。然而，在长期随访中，超过一半的患者在TPIAT后出现腹痛发作。这项工作的目的是描述这一复杂且不断增加的患者群体中腹痛的一系列原因。
方法
我们与本机构的专家进行了多学科讨论，并在可行的情况下查阅文献，以确定和描述TPIAT后腹痛的各种原因。
结果
我们确定了TPIAT后15种不同的腹痛原因，并描述了它们的表现、检查和处理方法。
结论
随着越来越多的患者接受TPIAT，我们必须在短期和长期内规划并解决因解剖和生理改变而导致的相关腹痛原因。
Zotero 插件