• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Letter re: Molecular characterization of HER2-negative breast cancers reveals a distinct patient subgroup with 17q12 deletion and heterozygous loss of ERBB2.

作者信息

Önder Arif Hakan

机构信息

Department of Medical Oncology, Antalya Training and Research Hospital, Antalya, Türkiye.

出版信息

ESMO Open. 2025 May;10(5):105074. doi: 10.1016/j.esmoop.2025.105074. Epub 2025 May 6.

DOI:10.1016/j.esmoop.2025.105074
PMID:40334316
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12167876/
Abstract
摘要

相似文献

1
Letter re: Molecular characterization of HER2-negative breast cancers reveals a distinct patient subgroup with 17q12 deletion and heterozygous loss of ERBB2.关于:HER2阴性乳腺癌的分子特征揭示了一个具有17q12缺失和ERBB2杂合性缺失的独特患者亚组的信件
ESMO Open. 2025 May;10(5):105074. doi: 10.1016/j.esmoop.2025.105074. Epub 2025 May 6.
2
Response to letter re: Molecular characterization of HER2 negative breast cancers reveals a distinct patient subgroup with 17q12 deletion and heterozygous loss of ERBB2.对关于“HER2阴性乳腺癌的分子特征揭示了一个具有17q12缺失和ERBB2杂合性缺失的独特患者亚组”信件的回复
ESMO Open. 2025 May;10(5):105075. doi: 10.1016/j.esmoop.2025.105075. Epub 2025 May 8.
3
Molecular characterization of HER2-negative breast cancers reveals a distinct patient subgroup with 17q12 deletion and heterozygous loss of ERBB2.HER2阴性乳腺癌的分子特征揭示了一个具有17q12缺失和ERBB2杂合性缺失的独特患者亚组。
ESMO Open. 2025 Feb;10(2):104111. doi: 10.1016/j.esmoop.2024.104111. Epub 2025 Jan 17.
4
Classification of HER2-negative breast cancers by copy number alteration status reveals molecular differences associated with chromosome 17 gene aberrations.根据拷贝数改变状态对HER2阴性乳腺癌进行分类,揭示了与17号染色体基因畸变相关的分子差异。
Ther Adv Med Oncol. 2023 Oct 31;15:17588359231206259. doi: 10.1177/17588359231206259. eCollection 2023.
5
Assessment of ERBB2/HER2 Status in HER2-Equivocal Breast Cancers by FISH and 2013/2014 ASCO-CAP Guidelines.采用 FISH 法和 2013/2014 年 ASCO-CAP 指南评估 HER2 结果不确定的乳腺癌中 ERBB2/HER2 状态。
JAMA Oncol. 2019 Mar 1;5(3):366-375. doi: 10.1001/jamaoncol.2018.6012.
6
Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies.整合 ERBB2 扩增型乳腺癌的分子和功能特征分析,鉴定出新的遗传依赖性。
Oncogene. 2014 Jan 30;33(5):619-31. doi: 10.1038/onc.2012.625. Epub 2013 Jan 21.
7
Comparison of Clinical Subtypes of Breast Cancer within the Claudin-Low Molecular Cluster Reveals Distinct Phenotypes.紧密连接蛋白低表达分子簇内乳腺癌临床亚型的比较揭示了不同的表型。
Cancers (Basel). 2023 May 10;15(10):2689. doi: 10.3390/cancers15102689.
8
New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays.通过cDNA微阵列在乳腺癌的ERBB2扩增子中发现的新的扩增且高表达基因。
Cancer Res. 2001 Nov 15;61(22):8235-40.
9
Intrinsic Subtype Switching and Acquired ERBB2/HER2 Amplifications and Mutations in Breast Cancer Brain Metastases.乳腺癌脑转移中的内在亚型转换以及获得性 ERBB2/HER2 扩增和突变。
JAMA Oncol. 2017 May 1;3(5):666-671. doi: 10.1001/jamaoncol.2016.5630.
10
Concomitant gastrin and ERBB2 gene amplifications at 17q12-q21 in the intestinal type of gastric cancer.肠型胃癌中17q12-q21处胃泌素与ERBB2基因的同时扩增
Genes Chromosomes Cancer. 1999 Jan;24(1):24-9. doi: 10.1002/(sici)1098-2264(199901)24:1<24::aid-gcc4>3.0.co;2-h.

本文引用的文献

1
Molecular characterization of HER2-negative breast cancers reveals a distinct patient subgroup with 17q12 deletion and heterozygous loss of ERBB2.HER2阴性乳腺癌的分子特征揭示了一个具有17q12缺失和ERBB2杂合性缺失的独特患者亚组。
ESMO Open. 2025 Feb;10(2):104111. doi: 10.1016/j.esmoop.2024.104111. Epub 2025 Jan 17.
2
Dissecting the biological heterogeneity of HER2-positive breast cancer.解析 HER2 阳性乳腺癌的生物学异质性。
Breast. 2021 Oct;59:339-350. doi: 10.1016/j.breast.2021.07.019. Epub 2021 Aug 5.
3
Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies.整合 ERBB2 扩增型乳腺癌的分子和功能特征分析,鉴定出新的遗传依赖性。
Oncogene. 2014 Jan 30;33(5):619-31. doi: 10.1038/onc.2012.625. Epub 2013 Jan 21.
4
Activating HER2 mutations in HER2 gene amplification negative breast cancer.在 HER2 基因扩增阴性乳腺癌中激活 HER2 突变。
Cancer Discov. 2013 Feb;3(2):224-37. doi: 10.1158/2159-8290.CD-12-0349. Epub 2012 Dec 7.