Wu Ping, Jin Long, Jiang Wanying, Zhou Yingzhang, Lin Lisheng, Lin Hongxin, Chen Hu
College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou, 350007, China.
Department of Pathology, Fujian Provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, Fujian, China.
Biosens Bioelectron. 2025 Sep 1;283:117522. doi: 10.1016/j.bios.2025.117522. Epub 2025 Apr 28.
Wound management plays a crucial role in nursing care as it facilitates effective wound healing and prevents infections. To overcome limitations associated with traditional treatment methods, various smart bandages have been developed. The monitoring of wound parameters and the implementation of targeted treatments are crucial aspects of smart bandage development. Smart bandages, as cutting-edge flexible wearable medical devices, integrate various sensing technologies, providing new insights for dynamic monitoring and personalized treatment of chronic wounds. This paper systematically summarizes the applications and developments of smart bandages in monitoring wound environmental parameters, focusing on two major detection methods: colorimetric sensing and electrochemical sensing. Colorimetric sensors typically rely on color changes induced by physiological parameters, which can not only be identified by the naked eye but also combined with image recognition algorithms for physiological parameter detection. Electrochemical sensors, on the other hand, modify electrodes with specific enzymes and detect physiological parameters through the electrical signals generated by redox reactions. In addition to sensing, this paper further explores the integrated application of three smart therapeutic strategies in smart bandages, including promoting cell proliferation and angiogenesis through electrical stimulation, achieving controlled drug release via responsive materials, and utilizing photothermal materials for efficient antibacterial treatment of wounds. Finally, the paper delves into the challenges these bandages face in system integration and clinical translation, and discusses their potential in personalized wound care.
伤口管理在护理中起着至关重要的作用，因为它有助于伤口有效愈合并预防感染。为了克服传统治疗方法的局限性，人们开发了各种智能绷带。伤口参数监测和靶向治疗的实施是智能绷带开发的关键方面。智能绷带作为前沿的柔性可穿戴医疗设备，集成了多种传感技术，为慢性伤口的动态监测和个性化治疗提供了新的见解。本文系统总结了智能绷带在监测伤口环境参数方面的应用和发展，重点介绍了两种主要检测方法：比色传感和电化学传感。比色传感器通常依赖于生理参数引起的颜色变化，这些变化不仅可以通过肉眼识别，还可以与图像识别算法相结合用于生理参数检测。另一方面，电化学传感器用特定酶修饰电极，并通过氧化还原反应产生的电信号检测生理参数。除了传感，本文还进一步探讨了三种智能治疗策略在智能绷带中的集成应用，包括通过电刺激促进细胞增殖和血管生成、通过响应材料实现药物控释以及利用光热材料对伤口进行高效抗菌治疗。最后，本文深入探讨了这些绷带在系统集成和临床转化方面面临的挑战，并讨论了它们在个性化伤口护理中的潜力。
