Kohan-Fortuna-Figueira S, Latorre M, Dardanelli P, Halliburton C, Bosio S, Puigdevall M
Scoliosis and Pediatric Orthopedic Center, «Carlos Ottolenghi» Orthopedic and Traumatology Institute, Hospital Italiano de Buenos Aires. Buenos Aires, Argentina.
Acta Ortop Mex. 2025 Mar-Apr;39(2):117-120.
musculoskeletal involvement of the extremities is common in pediatric patients with acute lymphoblastic leukemia. The insidious and oligosymptomatic presentation of several musculoskeletal conditions in these patients often leads to different diagnostic suspicions, which may delay appropriate management of the pathology. Non-albicans Candida osteoarticular infections are a rare entity that may affect immunodeficient patients. We describe a case of osteoarticular infection caused by an opportunistic fungus in a pediatric patient with acute lymphoblastic leukemia during the second week of rest post-consolidation block.
we present a case of a 4-year-old girl diagnosed with B-cell acute lymphoblastic leukemia that developed an elbow infection by Candida tropicalis. Two surgical debridements of the elbow, combined with the administration of antifungals, were required to control the infection. She fully recovered at six months postoperatively and remains without osteoarticular sequelae at three years of follow up.
C. tropicalis infection should be included in the differential diagnosis of osteoarticular complications in immunocompromised patients with acute lymphoblastic leukemia (ALL). Prompt diagnosis and treatment are essential to avoid osteoarticular sequelae.
四肢肌肉骨骼受累在急性淋巴细胞白血病患儿中很常见。这些患者中几种肌肉骨骼疾病的隐匿性和症状轻微的表现常常导致不同的诊断怀疑,这可能会延迟对该病症的适当治疗。非白色念珠菌性骨关节感染是一种罕见的疾病,可能会影响免疫功能低下的患者。我们描述了一例在巩固治疗阶段休息的第二周,一名患有急性淋巴细胞白血病的儿科患者发生机会性真菌感染导致的骨关节感染病例。
我们报告了一例4岁女孩,诊断为B细胞急性淋巴细胞白血病,发生了热带念珠菌引起的肘部感染。为控制感染,需要对肘部进行两次手术清创,并联合使用抗真菌药物。她在术后六个月完全康复,随访三年时仍无骨关节后遗症。
热带念珠菌感染应纳入免疫功能低下的急性淋巴细胞白血病(ALL)患者骨关节并发症的鉴别诊断中。及时诊断和治疗对于避免骨关节后遗症至关重要。