Ohkohchi N, Igarashi Y, Abe H, Ohi R, Kasai M
Nihon Geka Gakkai Zasshi. 1985 Jun;86(6):762-9.
The nutritional conditions and absorptive capacity of nine infants with short bowel syndrome were investigated during a long follow-up period from one and half years to 14 years and 7 months. The length of the residual small intestine ranged between 13 and 90cm. The nine infants had normal meals at home and did not suffer from persistent diarrhea. Most of the infants were thin. Nutritional conditions, for example, serum protein, triglycerides, vitamins, trace elements and plasma amino acids, were kept relatively well, and there were no symptoms of deficiency. The results of D-xylose absorption test had gradually improved but the absorptive capacity of sugars and amino acids observed by potential differences were within the normal limits or slightly subnormal except one infant. This indicated that the absorptive capacity of sugars and amino acids per a given area of the residual small intestine did not increase. From our examination the critical length of intestine might be in the neighborhood of 50cm. The infants left with less than 50cm of small intestine seem to have grown up normally but malabsorption of fat, sugars and bile acids have continued for many years.
对9例短肠综合征婴儿的营养状况和吸收能力进行了长达1年半至14年7个月的随访研究。残余小肠长度在13至90厘米之间。这9例婴儿在家中饮食正常,无持续性腹泻。多数婴儿消瘦。营养状况,如血清蛋白、甘油三酯、维生素、微量元素和血浆氨基酸等保持相对良好,无缺乏症状。D-木糖吸收试验结果逐渐改善,但除1例婴儿外,通过电位差观察到的糖和氨基酸吸收能力在正常范围内或略低于正常。这表明残余小肠单位面积的糖和氨基酸吸收能力并未增加。根据我们的检查,肠道临界长度可能在50厘米左右。小肠长度不足50厘米的婴儿似乎正常成长,但脂肪、糖和胆汁酸吸收不良持续多年。