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2024年流感前季节12个月及以下儿童的细支气管炎:病例系列

Bronchiolitis in children ≤ 12 months during the pre-flu season of 2024: A case series.

作者信息

Brits Marietjie, Brits Hanneke

机构信息

Department of Family Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein.

出版信息

S Afr Fam Pract (2004). 2025 Apr 17;67(1):e1-e4. doi: 10.4102/safp.v67i1.6109.

Abstract

BACKGROUND

In March 2024, the National Institute for Communicable Diseases (NICD) warned against a respiratory syncytial virus (RSV) outbreak during the pre-flu season, 2024. Globally, RSV is responsible for most respiratory infections in young children. Since April 2024, we have noticed a more severe presentation of children with bronchiolitis at the National District Hospital, Bloemfontein. We aimed to investigate the causative organism/s and the appropriateness of the treatment guidelines in our setting.

METHODS

A retrospective file review was carried out as part of the normal audit process. All children admitted with bronchiolitis during the 4-week study period were included in the case series. Ethical approval was obtained from relevant authorities.

RESULTS

Ten children ≤ 12 months presented with bronchiolitis symptoms. The Modified Tal Score was measured, with values between 8 and 12, indicating moderate and severe bronchiolitis in all cases. The demographics regarding gender, nutrition and vaccination status did not differ from previous years. Influenza A was identified in 60% of the cases, with RSV in only 20% of the cases. All the children responded well to symptomatic treatment and recovered.

CONCLUSION

Most bronchiolitis cases were caused not by the predicted RSV outbreak but by Influenza A.Contribution: Despite presenting with severe symptoms, all the children responded to symptomatic treatment as set out in our guidelines.

摘要

背景

2024年3月,国家传染病研究所(NICD)发出警告,2024年流感季前可能爆发呼吸道合胞病毒(RSV)疫情。在全球范围内,RSV是导致幼儿大多数呼吸道感染的原因。自2024年4月以来,我们注意到布隆方丹国家区医院患有细支气管炎的儿童症状更为严重。我们旨在调查致病病原体以及我们所在环境中治疗指南的适用性。

方法

作为正常审核流程的一部分,进行了回顾性病历审查。在为期4周的研究期间,所有因细支气管炎入院的儿童都被纳入该病例系列。已获得相关当局的伦理批准。

结果

10名12个月及以下的儿童出现了细支气管炎症状。测量了改良塔尔评分,分值在8至12之间,表明所有病例均为中度和重度细支气管炎。在性别、营养和疫苗接种状况方面的人口统计学数据与前几年没有差异。60%的病例中检测出甲型流感,只有20%的病例中检测出RSV。所有儿童对对症治疗反应良好并康复。

结论

大多数细支气管炎病例不是由预测的RSV疫情引起的,而是由甲型流感引起的。贡献:尽管症状严重,但所有儿童都按照我们的指南接受了对症治疗。

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