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掌握血气分析解读:基层医疗服务提供者实用指南

Mastering blood gas interpretation: A practical guide for primary care providers.

作者信息

Habib Talat, Nair Arun, Murphy Shane, Saeed Hamid, Ishaya Nyitiba

机构信息

Department of Family Medicine, Robert Mangaliso Sobukwe Hospital, Kimberley, South Africa; and, Department of Family Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein.

出版信息

S Afr Fam Pract (2004). 2025 Apr 23;67(1):e1-e7. doi: 10.4102/safp.v67i1.6058.

DOI:10.4102/safp.v67i1.6058
PMID:40336441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12067511/
Abstract

Accurate arterial blood gas (ABG) interpretation is essential for primary care providers (PCPs), especially in emergency and inpatient settings where timely, informed decisions can significantly impact patient outcomes. This review guides PCPs from basic to advanced interpretation through a systematic five-step approach for ABG analysis, focussing on oxygenation, pH status, and metabolic and respiratory disorders. Emphasising the recognition of complex acid-base disorders that may coexist even when pH appears normal, it incorporates tools such as delta and osmolar gap calculations to address multiple concurrent metabolic disturbances and clarify the interpretation of mixed acid-base conditions. The article also briefly considers the use of arterial and venous blood samples in clinical practice.

摘要

准确解读动脉血气(ABG)对基层医疗服务提供者(PCP)至关重要,尤其是在急诊和住院环境中,及时、明智的决策会显著影响患者的治疗结果。本综述通过一种系统的五步ABG分析方法,指导基层医疗服务提供者从基础解读到高级解读,重点关注氧合、pH状态以及代谢和呼吸紊乱。它强调认识到即使pH看似正常时也可能并存的复杂酸碱紊乱,纳入了诸如差值和渗透压间隙计算等工具,以处理多种并发的代谢紊乱并阐明对混合酸碱状况的解读。本文还简要探讨了临床实践中动脉血和静脉血样本的使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5a1/12067511/a7712419aebb/SAFP-67-6058-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5a1/12067511/11c2389b3bb3/SAFP-67-6058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5a1/12067511/a7712419aebb/SAFP-67-6058-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5a1/12067511/11c2389b3bb3/SAFP-67-6058-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5a1/12067511/a7712419aebb/SAFP-67-6058-g002.jpg

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本文引用的文献

1
A Systematic Approach to Understanding Acid-Base Disorders in the Critically Ill.一种理解危重症患者酸碱紊乱的系统方法。
Ann Pharmacother. 2024 Jan;58(1):65-75. doi: 10.1177/10600280231165787. Epub 2023 Apr 26.
2
Four Acid-Base Disturbances in a Critically-Ill Patient Undergoing Emergent Abdominal Surgery.一名接受急诊腹部手术的重症患者的四种酸碱平衡紊乱
Case Rep Crit Care. 2022 Jul 4;2022:1285598. doi: 10.1155/2022/1285598. eCollection 2022.
3
The arterial blood gas algorithm: Proposal of a systematic approach to analysis of acid-base disorders.
动脉血气分析算法:酸碱紊乱分析的系统方法建议。
Rev Esp Anestesiol Reanim (Engl Ed). 2020 Jan;67(1):20-34. doi: 10.1016/j.redar.2019.04.001. Epub 2019 Dec 9.
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A practical approach to understanding acid-base abnormalities in critical illness.
J Pharm Pract. 2011 Feb;24(1):17-26. doi: 10.1177/0897190010388153.
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Interpretation of arterial blood gas.动脉血气分析
Indian J Crit Care Med. 2010 Apr;14(2):57-64. doi: 10.4103/0972-5229.68215.
6
Serum anion gap: its uses and limitations in clinical medicine.血清阴离子间隙:其在临床医学中的应用及局限性
Clin J Am Soc Nephrol. 2007 Jan;2(1):162-74. doi: 10.2215/CJN.03020906. Epub 2006 Dec 6.
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Acid-base physiology: the 'traditional' and the 'modern' approaches.酸碱生理学:“传统”与“现代”方法
Anaesthesia. 2002 Apr;57(4):348-56. doi: 10.1046/j.0003-2409.2001.02447.x.
8
The delta (delta) gap: an approach to mixed acid-base disorders.Δ(德尔塔)间隙:一种处理混合性酸碱紊乱的方法。
Ann Emerg Med. 1990 Nov;19(11):1310-3. doi: 10.1016/s0196-0644(05)82292-9.