McGoldrick Mary G, Shah Chirag N
Columbia University Irving Medical Center, Department of Emergency Medicine, New York, NY.
Rutgers Robert Wood Johnson Medical School, Department of Emergency Medicine, New Brunswick, NJ.
J Educ Teach Emerg Med. 2025 Apr 30;10(2):V6-V9. doi: 10.21980/J8NW8G. eCollection 2025 Apr.
Myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction that can cause various symptoms provoking a visit to the emergency department (ED). In this case, we present a 54-year-old female who reported having her eyes "taped open" for the last two months. Her history and physical exam findings in the ED raised suspicion for MG. The patient was subsequently admitted and started on pyridostigmine. An elevated acetylcholinesterase receptor-binding antibody level confirmed the diagnosis of MG. This case report highlights the characteristic progressive weakness of facial muscles in MG, emphasizing the importance of early recognition of MG symptoms by emergency clinicians in order to initiate appropriate management and prevent respiratory compromise and morbidity.
Neurology, neurologic exam, myasthenia gravis, emergency medicine.
重症肌无力（MG）是一种神经肌肉接头的自身免疫性疾病，可导致各种症状，促使患者前往急诊科（ED）就诊。在本病例中，我们介绍了一名54岁女性，她报告称在过去两个月里眼睛一直“睁着贴起来”。她在急诊科的病史和体格检查结果引发了对重症肌无力的怀疑。患者随后入院并开始使用吡啶斯的明治疗。乙酰胆碱酯酶受体结合抗体水平升高证实了重症肌无力的诊断。本病例报告强调了重症肌无力中面部肌肉典型的进行性无力，强调了急诊临床医生早期识别重症肌无力症状的重要性，以便启动适当的治疗并预防呼吸功能不全和发病。
神经病学、神经检查、重症肌无力、急诊医学。
