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Too Much of a Good Thing? Cancer Risk and High Dose Folic Acid in Epilepsy.

作者信息

Munger Clary Heidi M

机构信息

Department of Neurology, Wake Forest University School of Medicine.

出版信息

Epilepsy Curr. 2025 May 5:15357597251335186. doi: 10.1177/15357597251335186.

DOI:10.1177/15357597251335186
PMID:40337186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12052737/
Abstract
摘要

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Too Much of a Good Thing? Cancer Risk and High Dose Folic Acid in Epilepsy.好事过头?癫痫患者的癌症风险与高剂量叶酸
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本文引用的文献

1
High-dose folic acid use and cancer risk in women who have given birth: A register-based cohort study.生育后女性高剂量叶酸使用与癌症风险:一项基于登记处的队列研究。
Epilepsia. 2025 Jan;66(1):75-88. doi: 10.1111/epi.18146. Epub 2024 Nov 14.
2
Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After In Utero Exposure to Antiseizure Medication: Practice Guideline From the AAN, AES, and SMFM.抗癫痫药物宫内暴露的致畸性、围产期和神经发育结局:AAN、AES 和 SMFM 的实践指南。
Neurology. 2024 Jun;102(11):e209279. doi: 10.1212/WNL.0000000000209279. Epub 2024 May 15.
3
Cancer Risk in Children of Mothers With Epilepsy and High-Dose Folic Acid Use During Pregnancy.母亲在孕期使用大剂量叶酸与儿童癌症风险。
JAMA Neurol. 2022 Nov 1;79(11):1130-1138. doi: 10.1001/jamaneurol.2022.2977.
4
Effects of periconceptional folate on cognition in children of women with epilepsy: NEAD study.孕期叶酸对女性癫痫患儿认知功能的影响:NEAD 研究。
Neurology. 2020 Feb 18;94(7):e729-e740. doi: 10.1212/WNL.0000000000008757. Epub 2019 Dec 23.
5
ACOG Committee Opinion No. 762: Prepregnancy Counseling.美国妇产科医师学会委员会意见 No.762:孕前咨询。
Obstet Gynecol. 2019 Jan;133(1):e78-e89. doi: 10.1097/AOG.0000000000003013.
6
Association of Folic Acid Supplementation During Pregnancy With the Risk of Autistic Traits in Children Exposed to Antiepileptic Drugs In Utero.妊娠期间补充叶酸与暴露于抗癫痫药物的儿童自闭症风险的关联。
JAMA Neurol. 2018 Feb 1;75(2):160-168. doi: 10.1001/jamaneurol.2017.3897.
7
Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society.实践参数更新:癫痫女性的管理问题——聚焦妊娠(循证综述):维生素K、叶酸、血药浓度及母乳喂养:美国神经病学学会和美国癫痫协会质量标准小组委员会及治疗与技术评估小组委员会报告
Neurology. 2009 Jul 14;73(2):142-9. doi: 10.1212/WNL.0b013e3181a6b325. Epub 2009 Apr 27.
8
Practice parameter [RETIRED]: management issues for women with epilepsy (summary statement). Report of the Quality Standards Subcommittee of the American Academy of Neurology.实践参数[已退休]:癫痫女性的管理问题(总结声明)。美国神经病学学会质量标准小组委员会报告。
Neurology. 1998 Oct;51(4):944-8. doi: 10.1212/wnl.51.4.944.
9
Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group.神经管缺陷的预防:医学研究委员会维生素研究结果。医学研究委员会维生素研究小组
Lancet. 1991 Jul 20;338(8760):131-7.