Patil Shankargouda, Miller Charles, Moffat Ryan, Janes Kade, Janes Brooklyn, Loomer Peter M, Licari Frank W
College of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT.
College of Graduate Studies, Roseman University of Health Sciences, South Jordan, UT.
J Patient Cent Res Rev. 2025 Apr 22;12(2):63-75. doi: 10.17294/2330-0698.2098. eCollection 2025 Spring.
Adjunctive use of photodynamic therapy in combination with scaling and root planing for periodontal maintenance offers an alternative to antibiotic therapy, potentially mitigating the risk of antibiotic resistance and its genotoxic or mutagenic effects. This systematic review analyzed studies, as of January 2023, that included the effects of a single application of photodynamic therapy in residual periodontal pockets with the probing depth and clinical attachment level as the primary and secondary outcomes, respectively.
PubMed, Scopus, and Web of Science databases, as well as the US National Institutes of Health and WHO Clinical Trials Registry, were searched for eligible studies on January 14, 2023.
Excluding non-English language articles, a total of nine studies examining 286 subjects were considered. Six of the nine studies resulted in decreased probing depth levels. Likewise, six of the nine studies exhibited a positive trend in terms of clinical attachment levels with photodynamic therapy. A limited number of studies revealed significant probing depth levels and clinical attachment levels after photodynamic therapy. The overall risk of bias was high in four studies, four studies showed some concerns regarding the study limitations, and one study had a low risk of bias.
Photodynamic therapy in combination with scaling and root planing may result in modest reductions in residual periodontal pocket depth levels and improvements in clinical attachment levels. The use of PDT in periodontal maintenance can reduce or eliminate the need for periodontal surgery, which may be more invasive and lead to a longer recovery time.
光动力疗法联合龈下刮治和根面平整用于牙周维护治疗，为抗生素治疗提供了一种替代方案，可能降低抗生素耐药性及其遗传毒性或致突变效应的风险。本系统评价分析了截至2023年1月的研究，这些研究包括单次应用光动力疗法对残余牙周袋的影响，以探诊深度和临床附着水平分别作为主要和次要结局。
于2023年1月14日在PubMed、Scopus和Web of Science数据库以及美国国立卫生研究院和世界卫生组织临床试验注册库中检索符合条件的研究。
排除非英文文章后，共纳入9项研究，涉及286名受试者。9项研究中有6项导致探诊深度降低。同样，9项研究中有6项在光动力疗法的临床附着水平方面呈现出积极趋势。少数研究显示光动力疗法后探诊深度和临床附着水平有显著变化。4项研究的总体偏倚风险较高，4项研究对研究局限性存在一些担忧，1项研究的偏倚风险较低。
光动力疗法联合龈下刮治和根面平整可能会使残余牙周袋深度适度降低，临床附着水平有所改善。在牙周维护治疗中使用光动力疗法可以减少或消除牙周手术的需求，牙周手术可能更具侵入性且恢复时间更长。
