西班牙巴利阿里群岛安达拉克斯市对严重急性呼吸综合征冠状病毒2（新冠病毒）的有效性筛查
Effectiveness screening of SARS-CoV-2 (COVID-19) in the municipality of Andratx (Balearic Islands, Spain).
作者信息
Monserrat-Mesquida Margalida, Quetglas-Llabrés Maria Magdalena, Bouzas Cristina, García Silvia, Font Patricia, Argelich Emma, Martínez Teresa, Sureda Antoni, Tur Josep A
机构信息
Research Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, Palma de Mallorca, Spain.
CIBEROBN (Physiopathology of Obesity and Nutrition), Instituto de Salud Carlos III, Madrid, Spain.
出版信息
Front Public Health. 2025 Apr 23;13:1461436. doi: 10.3389/fpubh.2025.1461436. eCollection 2025.
BACKGROUND
The coronavirus disease 2019 (COVID-19) pandemic was a global health emergency that significantly affected both the wellbeing of individuals and the global economy.
OBJECTIVE
The aim of this study was to evaluate the degree of SARS-CoV-2 involvement, viral load, and immunological response in adults aged 18-65 who performed essential tasks in the municipality of Andratx (Balearic Islands, Spain) compared to those who did not. Additionally, the study examined these factors in children aged 2-18 years from both groups, if there were any.
MATERIALS
Both groups were monitored between July 2020 and February 2021, in which the degree of involvement, the viral load, and the immunological response to the SARS-CoV-2 were analyzed using questionnaires, polymerase chain reaction (PCR) tests, and ELISA serology tests.
RESULTS
A positive case of RT-PCR test was found in screening the general population. The highest 2019-nCoV(N)-Ig antibody levels in plasma were measured from 1 to 17 February 2021, with the following percentage of positives: 6.8% of essential workers, 9.5% of essential workers' sons, 7.3% of non-essential workers, and 2.2% of non-essential workers' sons. However, an increase in levels of anti-SARS-CoV-2 (N) immunoglobulin G (IgG) and anti-SARS-CoV-2 (N) immunoglobulin M (IgM) were produced in session 3, from 9 to 25 November 2020, in both cases in non-essential workers, with a mean of 218.1 ng/mL of anti-SARS-CoV-2 (N) IgG and 31.3 ng/mL of anti-SARS-CoV-2 (N) IgM.
CONCLUSION
The control measures taken to manage the COVID-19 pandemic in the municipality of Andratx, Mallorca, Spain, were effective.
背景
2019年冠状病毒病（COVID-19）大流行是一场全球卫生突发事件，对个人福祉和全球经济都产生了重大影响。
目的
本研究旨在评估在西班牙巴利阿里群岛安达拉克斯市执行重要任务的18至65岁成年人与未执行重要任务的成年人相比，严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的感染程度、病毒载量和免疫反应。此外，该研究还检查了两组中2至18岁儿童的这些因素（如果有的话）。
材料
两组在2020年7月至2021年2月期间接受监测，通过问卷、聚合酶链反应（PCR）检测和酶联免疫吸附测定（ELISA）血清学检测分析SARS-CoV-2的感染程度、病毒载量和免疫反应。
结果
在对普通人群进行筛查时发现了1例逆转录聚合酶链反应（RT-PCR）检测呈阳性的病例。2021年2月1日至17日测量的血浆中2019新型冠状病毒（N）-Ig抗体水平最高，阳性百分比分别为：重要岗位工作人员的6.8%、重要岗位工作人员子女的9.5%、非重要岗位工作人员的7.3%和非重要岗位工作人员子女的2.2%。然而，在2020年11月9日至25日的第3阶段，非重要岗位工作人员的抗SARS-CoV-2（N）免疫球蛋白G（IgG）和抗SARS-CoV-2（N）免疫球蛋白M（IgM）水平均有所升高，抗SARS-CoV-2（N）IgG平均为218.1 ng/mL，抗SARS-CoV-2（N）IgM平均为31.3 ng/mL。
结论
西班牙马略卡岛安达拉克斯市为应对COVID-19大流行采取的防控措施是有效的。
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