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尼日利亚老年人髋部脆性骨折:一项关于出院后3个月和12个月时流行病学、活动能力及死亡率结局的回顾性研究

Fragility hip fractures among Nigerian older adults: a retrospective study of epidemiology, mobility and mortality outcomes at 3 and 12 months post-hospital discharge.

作者信息

Adesina Stephen Adesope, Amole Isaac Olusayo, Adefokun Imri Goodness, Adegoke Adepeju Olatayo, Ekunnrin Olusola Tunde, Akinwumi Akinsola Idowu, Ojo Simeon Ayorinde, Durodola Adewumi Ojeniyi, Ikem Innocent Chiedu, Eyesan Samuel Uwale

机构信息

Bowen University Teaching Hospital, P. O. Box 15, Ogbomoso, Oyo State, Nigeria.

Bowen University, P.M.B 284, Iwo, Osun State, Nigeria.

出版信息

Arch Osteoporos. 2025 May 8;20(1):61. doi: 10.1007/s11657-025-01553-0.

DOI:10.1007/s11657-025-01553-0
PMID:40338402
Abstract

UNLABELLED

Fragility hip fractures (FHFs) are a growing concern worldwide. Sub-Saharan Africa is no exception. Nigeria has limited data on FHFs. This study found that surgical treatment significantly enhances mobility and survival rates for older adults with FHFs. The findings can inform healthcare policies and practices in Nigeria and similar contexts.

PURPOSE

The global population, including that of sub-Saharan Africa, is rapidly ageing, resulting in a higher incidence of fragility fractures. This study investigates the epidemiology of fragility hip fractures (FHFs) at a Nigerian teaching hospital, focusing on the predictors of two key outcomes: (1) mobility and mortality 3 months post-discharge, and (2) mortality 12 months post-discharge.

METHODS

A retrospective study was conducted involving 102 older adults aged ≥ 60 who received treatment for femoral neck, intertrochanteric, and subtrochanteric fractures at a mission teaching hospital in Nigeria over 6 years. Data collected included demographics, causes of fractures, comorbidities, treatment methods, time-to-surgery, length of stay, mobility, and mortality rates. Univariate analyses were performed to identify mobility and mortality outcomes predictors at 3 and 12 months post-discharge.

RESULTS

The mean age was 78.0 years, with 49.0% of patients in the oldest-old category. 70.6% regained mobility 3 months post-discharge. The mortality rate was 3.9% at 3 months and 22.5% at 12 months. Predictors of better mobility and mortality outcomes included younger age, no/mild comorbidities, fractures due to community falls, femoral neck fractures, surgical treatment, and shorter time to surgery. Patients who regained mobility by 3 months had a lower 12-month mortality rate (p < 0.001).

CONCLUSION

This study emphasizes the importance of effective surgical management for FHFs in Nigeria's ageing population. The findings suggest that a multidisciplinary care approach, encompassing comprehensive management of comorbidities, age-friendly housing design, ongoing research, and investment in healthcare infrastructure, is essential to address the growing burden of FHFs.

摘要

未标注

髋部脆性骨折(FHFs)在全球范围内日益受到关注。撒哈拉以南非洲地区也不例外。尼日利亚关于FHFs的数据有限。本研究发现,手术治疗可显著提高患有FHFs的老年人的活动能力和生存率。这些发现可为尼日利亚及类似环境下的医疗政策和实践提供参考。

目的

全球人口,包括撒哈拉以南非洲地区的人口,正在迅速老龄化,导致脆性骨折的发病率更高。本研究调查了尼日利亚一家教学医院髋部脆性骨折(FHFs)的流行病学情况,重点关注两个关键结果的预测因素:(1)出院后3个月的活动能力和死亡率,以及(2)出院后12个月的死亡率。

方法

进行了一项回顾性研究,涉及102名年龄≥60岁的老年人,他们在尼日利亚一家教会教学医院接受了股骨颈、转子间和转子下骨折的治疗,为期6年。收集的数据包括人口统计学信息、骨折原因、合并症、治疗方法、手术时间、住院时间、活动能力和死亡率。进行单因素分析以确定出院后3个月和12个月时活动能力和死亡率结果的预测因素。

结果

平均年龄为78.0岁,49.0%的患者属于最年长者类别。70.6%的患者在出院后3个月恢复了活动能力。3个月时的死亡率为3.9%,12个月时为22.5%。活动能力和死亡率结果较好的预测因素包括年龄较小、无/轻度合并症、因社区跌倒导致的骨折、股骨颈骨折、手术治疗以及较短的手术时间。在3个月时恢复活动能力的患者12个月死亡率较低(p<0.001)。

结论

本研究强调了有效手术管理对尼日利亚老年人口中FHFs的重要性。研究结果表明,采取多学科护理方法,包括合并症的综合管理、适合老年人的住房设计、持续研究以及对医疗基础设施的投资,对于应对日益增加的FHFs负担至关重要。

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