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头颈部主动脉CT血管造影在急性A型主动脉夹层患者中的指导作用

The Guidance of Head-Neck-Aorta CT Angiography in Acute Type A Aortic Dissection Patients.

作者信息

Zhao Hongliang, Li Chengxiang, Xu Jian, Xue Chao, Chang Yingjuan, Wei Mengqi, Shang Lei, Lin Shushen, Duan Weixun, Zheng Minwen

机构信息

Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

Department of Cardiovascular Surgery, Affiliated Hospital of Qingdao University, Qingdao, China.

出版信息

JACC Asia. 2025 May;5(5):679-688. doi: 10.1016/j.jacasi.2024.12.011. Epub 2025 Feb 25.

Abstract

BACKGROUND

The benefit of preoperative craniocervical artery imaging has not been elucidated for decision-making during the surgical repair of acute type A aortic dissection (ATAAD).

OBJECTIVES

The purpose of this study was to explore the clinical implication of a preoperative extended head-neck-aorta computed tomography angiography (CTA) among ATAAD patients.

METHODS

ATAAD patients undergoing surgical repair were retrospectively enrolled. Preoperatively, 215 patients underwent aortic CTA (conventional group) and 220 underwent extended CTA (extended group). In the extended group, the surgical team was informed of assessment of craniocervical arteries before the operation. The primary endpoint was postoperative transient neurological deficit and permanent neurological deficit. A 1:1 propensity score matching analysis was performed to account for baseline differences between groups, resulting in 154 pairs.

RESULTS

In the extended group, 135 patients were free of preoperative neurological symptoms, but 35 (25.9%) presented with severely stenosed or occluded common carotid artery. Common carotid artery reconstruction and cannulation combined with femoral artery cannulation (24.1% vs 5.1%; P < 0.001) and bilateral antegrade selective cerebral perfusion during hypothermic circulatory arrest (56.4% vs 19.1%; P < 0.001) were more adopted in the extended group. In the matched cohort, the extended CTA was significantly associated with fewer postoperative permanent neurological deficit (adjusted OR: 0.186; 95% CI: 0.059-0.587; P = 0.004) after adjustment with logistic regression.

CONCLUSIONS

The extended head-neck-aorta CTA protocol provided additional anatomical clarity preoperatively for modified surgical strategies and may subsequently improved the neurological outcomes of ATAAD.

摘要

背景

术前颅颈动脉成像对急性A型主动脉夹层(ATAAD)手术修复决策的益处尚未阐明。

目的

本研究旨在探讨术前扩大范围的头颈部主动脉计算机断层扫描血管造影(CTA)在ATAAD患者中的临床意义。

方法

回顾性纳入接受手术修复的ATAAD患者。术前,215例患者接受了主动脉CTA(传统组),220例接受了扩大范围的CTA(扩大组)。在扩大组中,手术团队在术前被告知对颅颈动脉进行评估。主要终点是术后短暂性神经功能缺损和永久性神经功能缺损。进行1:1倾向评分匹配分析以考虑组间基线差异,最终得到154对匹配病例。

结果

在扩大组中,135例患者术前无神经症状,但35例(25.9%)出现严重狭窄或闭塞的颈总动脉。扩大组更常采用颈总动脉重建和插管联合股动脉插管(24.1%对5.1%;P<0.001)以及在低温循环停止期间进行双侧顺行选择性脑灌注(56.4%对19.1%;P<0.001)。在匹配队列中,经逻辑回归调整后,扩大CTA与术后永久性神经功能缺损较少显著相关(调整后的OR:0.186;95%CI:0.059 - 0.587;P = 0.004)。

结论

扩大范围的头颈部主动脉CTA方案在术前为改良手术策略提供了额外的解剖学清晰度,并可能随后改善ATAAD的神经学结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4db/12081269/bc44d07653d3/ga1.jpg

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