Scarpetta Maia, Kanner Rachel, Menezes Neia Prata, McDonell Claire C, Bruneau Julie, Page Kimberly, Morris Meghan D
Department of Epidemiology and Biostatistics, University of California, San Francisco, Box 1224, San Francisco, CA, 550 16thStreet94158, USA.
Department of Medicine, University of California San Francisco, San Francisco, USA.
BMC Public Health. 2025 May 8;25(1):1707. doi: 10.1186/s12889-025-22781-6.
People who inject drugs (PWID) face a substantial risk of hepatitis C virus (HCV) infection, often in the context of multiple injecting partnerships. The disclosure of HCV status to injecting partners holds significant implications for prevention and care among PWID.
We used cross-sectional dyadic survey data (collected from both members of injecting partnerships) to estimate the prevalence of HCV-status disclosure between PWID and their injecting partners, overall and by partnership HCV infection status.
Across the two study sites (San Francisco and Montreal), 91% of participants self-reported receiving an HCV test, resulting in 162 individuals and 131 partnerships. A majority (57%) self-reported being HCV positive. HCV status disclosure was prevalent overall (79%) and was most common (41%) with partnerships where both partners' status was positive (+ / +) but less common (17%) when one partner was positive ( ±) and when neither partner was positive (-/-) (32%); no disclosure was more common when both partners were negative (-/-) (50%).
Overall, our study demonstrated a high prevalence of HCV testing and subsequent disclosure of HCV status within injecting partnerships. This presents an opportunity to leverage these relationships for treatment linkage and prevention messaging.
注射吸毒者面临感染丙型肝炎病毒(HCV)的重大风险,且往往是在多个注射伙伴关系的背景下。向注射伙伴披露HCV感染状况对注射吸毒者的预防和护理具有重大意义。
我们使用横断面二元调查数据(从注射伙伴关系的双方收集)来估计注射吸毒者与其注射伙伴之间HCV感染状况披露的患病率,总体情况以及按伙伴关系的HCV感染状况进行分析。
在两个研究地点(旧金山和蒙特利尔),91%的参与者自我报告接受了HCV检测,共涉及162个人和131个伙伴关系。大多数(57%)自我报告HCV呈阳性。HCV感染状况披露总体上较为普遍(79%),在双方感染状况均为阳性(+/+)的伙伴关系中最为常见(41%),但在一方为阳性(±)以及双方均为阴性(-/-)的伙伴关系中则不太常见(分别为17%和32%);在双方均为阴性(-/-)的伙伴关系中,未披露感染状况更为常见(50%)。
总体而言,我们的研究表明在注射伙伴关系中HCV检测及随后的感染状况披露较为普遍。这为利用这些关系促进治疗衔接和预防宣传提供了契机。