Mekonnen Y, Wolde E, Hagos T, Yared K, Bekele A, Mehari Z, Abebe S, Tadesse Y, Taye T, Asire G, Nigatu T, Kumar S, Girma S
Mela Research, P.O. Box 34422, Addis Ababa, Ethiopia.
Children's Investment Fund Foundation (CIFF), London, UK.
BMC Health Serv Res. 2025 May 8;25(1):662. doi: 10.1186/s12913-025-12789-4.
Antenatal care (ANC) in Ethiopia faces quality and content gaps. The Enhancing Nutrition and Antenatal Infection Treatment (ENAT) intervention was designed to improve ANC services in public health facilities by strengthening infection diagnosis, training healthcare providers, supplying equipment, and enhancing counseling. We assessed ENAT's association with improved ANC outcomes, including testing (blood/urine), infection prevention, nutrition supplementation, counseling, and visit adherence.
A quasi-experimental design (QED) was used, with baseline data collected in December 2020 and endline in January 2023 from intervention and comparison areas. We interviewed women who were pregnant within two years preceding the surveys: baseline (comparison = 631, intervention = 705) and endline (comparison = 638, intervention = 719). We examined the association between the intervention and ANC outcomes using Difference-in-Differences (DiD) logit models.
The ENAT intervention showed statistically significant improvements in blood sample testing during pregnancy (DiD: +8%, β = 1.03, p < 0.001), while urine testing demonstrated a marginally significant association (DiD: +7%, β = 0.60, p = 0.057). Notable positive improvements were observed in the administration of iron folate (DiD, + 11%, β = 1.21, p < 0.001), tetanus toxoid injections (DiD, + 10%, β = 0.61, p = 0.042), and deworming tablets (DiD, + 20%, β = 0.65, p = 0.032). Statistically significant improvements were also seen in counseling on nutrition (DiD, + 11%, β = 0.59, p = 0.001) and pregnancy complications (DiD, + 9%, β = 0.34, p = 0.038). Although four or more ANC visits saw a statistically significant increase in the intervention area (DiD: +9%, β = 1.24, p = 0.049), 38% of women remained below this benchmark. Furthermore, the intervention did not significantly improve the timing of the first ANC visit (DiD, + 5%, β = 0.017, p = 0.928), with only half of the women initiating ANC in the first trimester.
The ENAT intervention improved ANC service contents, quality, and visit frequency while enhancing key counseling topics. These findings demonstrate targeted interventions' potential to strengthen ANC in resource-limited settings. However, early ANC initiation remains challenging, with many women not completing the recommended four or more visits. Future programs should address barriers to timely ANC initiation and completion.
埃塞俄比亚的产前保健(ANC)存在质量和内容方面的差距。加强营养与产前感染治疗(ENAT)干预措施旨在通过强化感染诊断、培训医疗服务提供者、供应设备以及加强咨询来改善公共卫生机构的产前保健服务。我们评估了ENAT与改善产前保健结果之间的关联,包括检测(血液/尿液)、感染预防、营养补充、咨询以及就诊依从性。
采用准实验设计(QED),于2020年12月收集干预地区和对照地区的基线数据,并于2023年1月收集终末数据。我们对在调查前两年内怀孕的女性进行了访谈:基线期(对照组=631人,干预组=705人)和终末期(对照组=638人,干预组=719人)。我们使用双重差分(DiD)逻辑模型检验了干预措施与产前保健结果之间的关联。
ENAT干预措施在孕期血液样本检测方面显示出具有统计学意义的改善(DiD:+8%,β=1.03,p<0.001),而尿液检测显示出边缘显著关联(DiD:+7%,β=0.60,p=0.057)。在铁叶酸给药(DiD,+11%,β=1.21,p<0.001)、破伤风类毒素注射(DiD,+10%,β=0.61,p=0.042)和驱虫片(DiD,+20%,β=0.65,p=0.032)方面观察到显著的积极改善。在营养咨询(DiD,+11%,β=0.59,p=0.001)和妊娠并发症咨询(DiD,+9%,β=0.34,p=0.038)方面也观察到具有统计学意义的改善。尽管干预地区四次或更多次产前保健就诊人数有统计学意义的增加(DiD:+9%,β=1.24,p=0.049),但仍有38%的女性未达到这一基准。此外,干预措施并未显著改善首次产前保健就诊的时间(DiD,+5%,β=0.017,p=0.928),只有一半的女性在孕早期开始接受产前保健。
ENAT干预措施改善了产前保健服务内容、质量和就诊频率,同时加强了关键的咨询主题。这些发现表明,有针对性的干预措施在资源有限的环境中加强产前保健方面具有潜力。然而,早期开始接受产前保健仍然具有挑战性,许多女性未完成推荐的四次或更多次就诊。未来的项目应解决及时开始和完成产前保健的障碍。