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肠道之外:便秘对社区居住老年人功能活动能力和生活质量的被忽视影响——一项横断面研究

Beyond the gut: The overlooked impact of constipation on functional mobility and quality of life in community-dwelling elders - a cross-sectional study.

作者信息

Oztop Mucahit, Yagcı Nesrin

机构信息

Physiotherapy and Rehabilitation Department, Faculty of Health Science, Burdur Mehmet Akif Ersoy University, Burdur, Turkiye.

School of Physical Therapy and Rehabilitation, Pamukkale University, Denizli, Turkiye.

出版信息

Geriatr Gerontol Int. 2025 Jun;25(6):799-805. doi: 10.1111/ggi.70060. Epub 2025 May 8.

DOI:10.1111/ggi.70060
PMID:40343404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12170964/
Abstract

AIM

Constipation is common in the elderly and may impair functional mobility. This study examined its prevalence and impact on mobility in community-dwelling elders.

METHODS

A total of 630 elders (340 females, 290 males; mean age 70.78 ± 4.88 years) with adequate cognitive function were evaluated. Constipation was defined via self-report according to the Rome IV criteria and quantified with the Constipation Severity Instrument (CSI). Lower limb mobility was measured using the Five-Times Sit-to-Stand Test (FTSST), while rectal pain and quality of life (QoL) were assessed using 10-cm visual analog scales.

RESULTS

Constipation was self-reported by 82.7% of participants. Compared with non-constipated elders, those with constipation had significantly prolonged FTSST times, higher rectal pain scores, and lower QoL (all P < 0.001). Correlation analysis revealed that greater constipation severity (CSI scores) was strongly associated with poorer QoL (r = 0.71, P < 0.001) and rectal pain (r = 0.87, P < 0.001), and negatively correlated with cognitive function (r = -0.14, P < 0.001). Additionally, CSI scores were positively correlated with FTSST time (r = 0.21, P < 0.001) and rectal pain (r = 0.69, P < 0.001).

CONCLUSIONS

Constipation in community-dwelling elders is strongly linked to increased rectal pain, reduced lower limb functional mobility, and poorer QoL. These results support the need for integrated gastrointestinal and physiotherapy interventions, and future studies should use longitudinal and interventional designs to confirm causality and optimize treatment strategies. Geriatr Gerontol Int 2025; 25: 799-805.

摘要

目的

便秘在老年人中很常见,可能会损害功能活动能力。本研究调查了社区居住老年人便秘的患病率及其对活动能力的影响。

方法

对630名认知功能正常的老年人(340名女性,290名男性;平均年龄70.78±4.88岁)进行了评估。根据罗马IV标准通过自我报告定义便秘,并使用便秘严重程度量表(CSI)进行量化。使用五次坐立试验(FTSST)测量下肢活动能力,同时使用10厘米视觉模拟量表评估直肠疼痛和生活质量(QoL)。

结果

82.7%的参与者自我报告有便秘。与无便秘的老年人相比,便秘患者的FTSST时间显著延长,直肠疼痛评分更高,生活质量更低(所有P<0.001)。相关分析显示,便秘严重程度越高(CSI评分)与生活质量越差(r=0.71,P<0.001)和直肠疼痛(r=0.87,P<0.001)密切相关,与认知功能呈负相关(r=-0.14,P<0.001)。此外,CSI评分与FTSST时间(r=0.21,P<0.001)和直肠疼痛(r=0.69,P<0.001)呈正相关。

结论

社区居住老年人的便秘与直肠疼痛增加、下肢功能活动能力降低和生活质量较差密切相关。这些结果支持了综合胃肠和物理治疗干预的必要性,未来的研究应采用纵向和干预性设计来确认因果关系并优化治疗策略。《老年医学与老年病学国际杂志》2025年;25:799-805。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05bc/12170964/a6455de2256f/GGI-25-799-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05bc/12170964/7bf1d0a51ec7/GGI-25-799-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05bc/12170964/a6455de2256f/GGI-25-799-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05bc/12170964/7bf1d0a51ec7/GGI-25-799-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05bc/12170964/a6455de2256f/GGI-25-799-g001.jpg

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本文引用的文献

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Medicine (Baltimore). 2023 Jun 30;102(26):e34160. doi: 10.1097/MD.0000000000034160.
2
Association Between Constipation and a Reduction in Lower Limb Muscle Strength in Preoperative Patients with Thoracic Spinal Tumors.胸段脊柱肿瘤术前患者便秘与下肢肌肉力量下降的相关性。
Chin Med Sci J. 2023 Jun 30;38(2):109-116. doi: 10.24920/004154.
3
The five times sit-to-stand test: safety, validity and reliability with critical care survivors's at ICU discharge.
五次坐立试验:对重症监护病房出院的危重症幸存者的安全性、有效性和可靠性
Arch Physiother. 2022 Dec 18;13(1):2. doi: 10.1186/s40945-022-00156-z.
4
Functional Constipation is Associated with a Decline in Word Recognition 2 Years Later in Community-Dwelling Older Adults: The Korean Frailty and Aging Cohort Study.功能性便秘与社区居住的老年人两年后单词识别能力下降有关:韩国衰弱与老龄化队列研究。
Ann Geriatr Med Res. 2022 Sep;26(3):241-247. doi: 10.4235/agmr.22.0092. Epub 2022 Sep 27.
5
Constipation is Associated With Mild Cognitive Impairment in Patients With de novo Parkinson's Disease.便秘与新发帕金森病患者的轻度认知障碍有关。
J Mov Disord. 2022 Jan;15(1):38-42. doi: 10.14802/jmd.21074. Epub 2021 Nov 17.
6
Status of Constipation and Its Association with Sarcopenia in Older Adults: A Population-Based Cohort Study.老年人便秘现状及其与肌少症的关系:一项基于人群的队列研究。
Int J Environ Res Public Health. 2021 Oct 21;18(21):11083. doi: 10.3390/ijerph182111083.
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