Ahmed Mohammad, Soofi Muhammad, Patel Maulin, White Ricarda, Nashed Catherine, Riela Steven, Nudy Matthew, Lee Aaron
Penn State Heart and Vascular Institute, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
Department of Anesthesiology and Perioperative Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
JACC Case Rep. 2025 May 7;30(9):103285. doi: 10.1016/j.jaccas.2025.103285. Epub 2025 Feb 26.
Coronary artery spasm (CAS) is a sudden, reversible narrowing of the lumen of the coronary arteries caused by spontaneous vascular smooth muscle hypercontractility. A 47-year-old woman with history of recurrent cardiac arrests presented after having a witnessed cardiac arrest requiring 3 shocks from her implantable cardioverter-defibrillator. She then suffered another cardiac arrest that resulted in hemodynamic instability requiring venoarterial extracorporeal membrane oxygenation. Coronary angiography demonstrated severe multivessel CAS that resolved with intracoronary nitroglycerin. A left stellate ganglion block was performed, and she was ultimately decannulated and discharged with a regimen of oral vasodilators. Reports of multivessel CAS leading to cardiac arrest are rare in the literature. Options for recurrent CAS refractory to medical therapy include left stellate ganglion block and sympathectomy.
冠状动脉痉挛(CAS)是一种由自发性血管平滑肌过度收缩引起的冠状动脉管腔突然、可逆性狭窄。一名47岁有反复心脏骤停病史的女性,在发生目击性心脏骤停后就诊,其植入式心脏复律除颤器需电击3次。随后她又发生了一次心脏骤停,导致血流动力学不稳定,需要进行静脉-动脉体外膜肺氧合。冠状动脉造影显示严重的多支血管CAS,经冠状动脉内注射硝酸甘油后缓解。进行了左侧星状神经节阻滞,她最终拔除插管,并采用口服血管扩张剂方案出院。文献中关于多支血管CAS导致心脏骤停的报道很少。对于药物治疗难治的复发性CAS,治疗选择包括左侧星状神经节阻滞和交感神经切除术。