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用于心房颤动的超高功率短程消融过程中的炭形成

Char Formation During Very High-Power Short-Duration Ablation for Atrial Fibrillation.

作者信息

Suga Kazumasa, Kato Hiroyuki, Yamazaki Koudai, Sakurai Taku, Ota Ryusuke, Ota Tomoyuki, Murakami Hisashi, Kada Kenji, Tsuboi Naoya, Yanagisawa Satoshi, Inden Yasuya, Murohara Toyoaki

机构信息

Department of Cardiology, Japan Community Healthcare Organization Chukyo Hospital, Nagoya, Japan.

Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

出版信息

J Cardiovasc Electrophysiol. 2025 Jul;36(7):1569-1578. doi: 10.1111/jce.16707. Epub 2025 May 9.

Abstract

INTRODUCTION

Pulmonary vein (PV) isolation using very high-power short-duration (vHPSD) radiofrequency catheter ablation is an effective treatment strategy for atrial fibrillation. However, PV isolation using vHPSD ablation (vHPSD-PVI) carries a potential risk of char formation. We aimed to assess the incidence, patient characteristics, and procedural factors of char formation during vHPSD-PVI.

METHODS AND RESULTS

Fifty consecutive patients scheduled to undergo initial PV isolation (PVI) were prospectively included. PVI was performed using a QDOT MICRO catheter in the vHPSD setting (90 W/4 s). PVs were divided into eight segments, and char formation around the ablation catheter was evaluated after the ablation of each segment. Patient characteristics and procedural parameters were analyzed to determine the risk factors for char formation. During vHPSD-PVI, char formation was observed in 24 (48.0%) patients, primarily at the groove between the tip and ring electrodes. Among the segments, the incidence of char formation was the highest (26.0%) in the anterior and posterior right inferior PV (RIPV) segments (p < 0.001). One patient with char formation developed symptomatic thromboembolism after the procedure. The left atrial volume index (LAVI) (odds ratio [OR], 1.089; 95% confidence interval [CI], 1.011-1.173; p = 0.024) and parallel catheter orientation (OR, 1.592; 95% CI, 1.416-1.791; p < 0.001) were independent predictors of char formation.

CONCLUSION

Char formation occurred in 48.0% of the patients during vHPSD-PVI. Application to the RIPV segment, a higher LAVI, and parallel catheter orientation were associated with an increased risk of char formation, indicating that vHPSD applications should be avoided under these conditions.

摘要

介绍

使用超高功率短持续时间(vHPSD)射频导管消融进行肺静脉(PV)隔离是心房颤动的一种有效治疗策略。然而,使用vHPSD消融进行PV隔离(vHPSD-PVI)存在炭化形成的潜在风险。我们旨在评估vHPSD-PVI期间炭化形成的发生率、患者特征和手术因素。

方法和结果

前瞻性纳入了50例计划进行初次PV隔离(PVI)的连续患者。在vHPSD设置(90W/4s)下使用QDOT MICRO导管进行PVI。将PV分为八个节段,在每个节段消融后评估消融导管周围的炭化形成情况。分析患者特征和手术参数以确定炭化形成的危险因素。在vHPSD-PVI期间,24例(48.0%)患者观察到炭化形成,主要位于尖端和环形电极之间的凹槽处。在这些节段中,右肺下静脉(RIPV)前后节段的炭化形成发生率最高(26.0%)(p<0.001)。1例有炭化形成的患者术后发生有症状的血栓栓塞。左心房容积指数(LAVI)(比值比[OR],1.089;95%置信区间[CI],1.011-1.173;p=0.024)和平行导管方向(OR,1.592;95%CI,1.416-1.791;p<0.001)是炭化形成的独立预测因素。

结论

vHPSD-PVI期间48.0%的患者发生炭化形成。应用于RIPV节段、较高的LAVI和平行导管方向与炭化形成风险增加相关,表明在这些情况下应避免vHPSD应用。

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