重复的CD107a染色能够识别连续脱颗粒的自然杀伤细胞。
Repeated CD107a Staining Enables Identification of Serial Degranulating NK Cells.
作者信息
Niemann Jens, Claus Maren, Imširović Vanna, Watzl Carsten
机构信息
Department for Immunology, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany.
Department of Histology and Embryology, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
出版信息
Eur J Immunol. 2025 May;55(5):e202451642. doi: 10.1002/eji.202451642.
Abstract
Upon repeated target cell contact serial degranulating NK cells are identified by multiple staining events using differentially labeled anti-CD107a (LAMP1) antibodies. This flow-cytometry-based method allows for the characterization and isolation of serial degranulating NK cells.
摘要
在反复与靶细胞接触后，通过使用不同标记的抗CD107a（溶酶体相关膜蛋白1）抗体进行多次染色事件来鉴定连续脱颗粒的自然杀伤（NK）细胞。这种基于流式细胞术的方法能够对连续脱颗粒的NK细胞进行表征和分离。
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