Suppr超能文献

Effects of naloxone and chlordiazepoxide on lateral hypothalamic self-stimulation in rats.

作者信息

Ichitani Y, Iwasaki T, Satoh T

出版信息

Physiol Behav. 1985 May;34(5):779-82. doi: 10.1016/0031-9384(85)90377-4.

DOI:10.1016/0031-9384(85)90377-4
PMID:4034718
Abstract

Lateral hypothalamic self-stimulation behavior of rats in an operant chamber was investigated under the treatments of the first injection of naloxone (5 mg/kg) or saline followed by the second injection of chlordiazepoxide (4 mg/kg) or saline. Both inhibitory effect of naloxone and facilitatory effect of chlordiazepoxide on self-stimulation response were statistically significant, but the interaction between the two effects was not obtained. The results indicate that the facilitatory effect of chlordiazepoxide upon self-stimulation is independent of endogenous opioid system. Further, the obtained effect of naloxone was discussed in terms of interaction of the drug with aversive, rather than rewarding, component of self-stimulation.

摘要

相似文献

1
Effects of naloxone and chlordiazepoxide on lateral hypothalamic self-stimulation in rats.
Physiol Behav. 1985 May;34(5):779-82. doi: 10.1016/0031-9384(85)90377-4.
2
Effects of chronic haloperidol and chlordiazepoxide treatment on lateral hypothalamic self-stimulation behavior in rats.慢性氟哌啶醇和氯氮卓治疗对大鼠下丘脑外侧自我刺激行为的影响。
Jpn J Pharmacol. 1984 Feb;34(2):131-5. doi: 10.1254/jjp.34.131.
3
Effects of chlordiazepoxide on the self-regulated duration of lateral hypothalamic stimulation in rats.氯氮卓对大鼠下丘脑外侧区刺激的自我调节持续时间的影响。
Psychopharmacology (Berl). 1983;81(3):236-8. doi: 10.1007/BF00427269.
4
Facilitation of self-stimulation of ventral tegmentum by microinjection of opioid receptor subtype agonists.通过微量注射阿片受体亚型激动剂促进腹侧被盖区的自我刺激
Physiol Behav. 1994 Apr;55(4):627-31. doi: 10.1016/0031-9384(94)90036-1.
5
Concurrent stimulation-induced place preference in lateral hypothalamus and parabrachial complex: differential effects of naloxone.外侧下丘脑和臂旁复合体的同时刺激诱导的位置偏爱：纳洛酮的差异作用。
Behav Brain Res. 2011 Nov 20;225(1):311-6. doi: 10.1016/j.bbr.2011.07.029. Epub 2011 Jul 22.
6
Naloxone blocks the excitatory effect of ethanol and chlordiazepoxide on lateral hypothalamic self-stimulation behavior.纳洛酮可阻断乙醇和氯氮卓对下丘脑外侧自我刺激行为的兴奋作用。
Life Sci. 1978 Oct 2;23(13):1359-64. doi: 10.1016/0024-3205(78)90394-6.
7
Asymmetrical effects of morphine and naloxone on reward mechanisms.吗啡和纳洛酮对奖赏机制的不对称作用。
Psychopharmacology (Berl). 1982;78(3):219-24. doi: 10.1007/BF00428154.
8
[Conditioned-reflex activation of electrical self-stimulation of the brain: a model of a situational craving for narcotics].
Zh Vyssh Nerv Deiat Im I P Pavlova. 1992 Jul-Aug;42(4):759-63.
9
Intracranial self-stimulation distinguishes between two benzodiazepine antagonists.
Neurosci Lett. 1984 Jun 15;47(2):173-7. doi: 10.1016/0304-3940(84)90425-7.
10
[Possible role of positive reinforcement zones in the mechanisms of pain regulation and their relation to the endogenous opiate system].
Biull Eksp Biol Med. 1987 May;103(5):577-9.

引用本文的文献

1
Interactions of naloxone with morphine, amphetamine and phencyclidine on fixed interval responding for intracranial self-stimulation in rats.纳洛酮与吗啡、苯丙胺和苯环利定对大鼠颅内自我刺激固定间隔反应的相互作用。
Psychopharmacology (Berl). 1990;102(2):263-8. doi: 10.1007/BF02245931.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验