U Pratibha Bhat, Ashraf Asem Ali, Roy Anulekha
Nitte (Deemed to be University), KS Hegde Medical Academy (KSHEMA), Department of Microbiology, Mangalore, Karnataka, India.
Diagn Microbiol Infect Dis. 2025 Sep;113(1):116885. doi: 10.1016/j.diagmicrobio.2025.116885. Epub 2025 May 2.
Melioidosis, caused by Burkholderia pseudomallei, presents with diverse clinical manifestations. This is a case of a 1-year-old female presenting with fever, and altered sensorium. Her MRI had revealed features suggestive of brainstem encephalitis. Cerebrospinal fluid analysis confirmed the presence of Burkholderia pseudomallei. Treatment involved a two-phase antibiotic therapy: the acute phase and the eradication phase, and after 14 days of appropriate antibiotics, the patient stabilized and was discharged with follow-up care. This case underscores the importance of recognizing the rare neurological presentation of neuromelioidosis in pediatric patients, emphasizing the need for timely diagnosis and treatment to improve outcomes.
类鼻疽病由类鼻疽伯克霍尔德菌引起,临床表现多样。这是一例1岁女性患者,表现为发热和意识改变。其磁共振成像(MRI)显示有脑干脑炎的特征。脑脊液分析证实存在类鼻疽伯克霍尔德菌。治疗采用两阶段抗生素疗法:急性期和根除期,在使用适当抗生素治疗14天后,患者病情稳定并出院接受随访护理。该病例强调了认识小儿神经类鼻疽病这种罕见神经表现的重要性,突出了及时诊断和治疗以改善预后的必要性。