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马来西亚背景下儿童免疫接种中的疫苗犹豫现象

Vaccine Hesitancy in Childhood Immunization in the Malaysian Context.

作者信息

Othman Nour H, Rajendram Santhanathan, Singh Helvinder K Balbir

机构信息

Department of Pharmacy, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Malaysia.

Department of Psychology, Faculty of Medicine, Royal College of Medicine Perak, Universiti Kuala Lumpur, Malaysia.

出版信息

J Pharm Bioallied Sci. 2024 Oct-Dec;16(4):121-125. doi: 10.4103/jpbs.jpbs_645_24. Epub 2025 Mar 26.

Abstract

The increase in vaccine-preventable infections in young children in Malaysia during the previous decade has been concerning. This is related to vaccine reluctance, which puts herd immunity at risk. This review evaluated the current situation and understanding of vaccine hesitancy (VH) in childhood immunization in Malaysia. A literature search was performed utilizing three databases, namely PubMed, Google Scholar, and Science Direct. The search included full-text papers published in English between January 2015 and October 2023 with specific keywords used. The narrative review included 15 articles. VH is premised on either refusal to vaccinate or delay in getting vaccination. There is a wide range of VH rates, and they differ widely by state and region. Delayed vaccination ranged from 0.03% to 21%, and refusal to vaccinate ranged from 0.08% to 42.5%. Predictors of VH include demographics, religion, lack of belief in vaccine benefits or safety, and a preference for homeopathic and complementary alternative therapies. Vaccine hesitation has recently been influenced by antivaccine propaganda and vaccine disinformation on social media. VH is an important problem that needs the attention of policymakers to avoid the recurrence of vaccine-preventable diseases. Nationwide research can help to provide a deeper understanding of the issue. Misinformation and disinformation about vaccines need to be countered. Monitoring of vaccination is necessary through a computerized registry that should be made available nationwide.

摘要

在过去十年中,马来西亚幼儿中疫苗可预防感染的增加令人担忧。这与疫苗犹豫有关,而疫苗犹豫会使群体免疫面临风险。本综述评估了马来西亚儿童免疫接种中疫苗犹豫(VH)的现状及认知情况。利用三个数据库进行了文献检索,即PubMed、谷歌学术和科学Direct。检索范围包括2015年1月至2023年10月期间以特定关键词发表的英文全文论文。叙述性综述纳入了15篇文章。VH的前提是拒绝接种疫苗或延迟接种。VH率范围广泛,且因州和地区而异。延迟接种的比例从0.03%到21%不等,拒绝接种的比例从0.08%到42.5%不等。VH的预测因素包括人口统计学特征、宗教信仰、对疫苗益处或安全性缺乏信任,以及对顺势疗法和补充替代疗法的偏好。疫苗犹豫最近受到了反疫苗宣传和社交媒体上疫苗虚假信息的影响。VH是一个需要政策制定者关注的重要问题,以避免疫苗可预防疾病的再次发生。全国性研究有助于更深入地了解该问题。需要反驳关于疫苗的错误信息和虚假信息。有必要通过全国范围内可用的计算机化登记系统对疫苗接种情况进行监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1878/12064000/6063f3be62a9/JPBS-16-121-g001.jpg

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