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探索活体肾供体的生活质量和社会影响:来自沙特阿拉伯三级医院的见解:一项2022年至2024年的为期两年的横断面研究。

Exploring quality of life and social impacts in living kidney donors: Insights from tertiary hospitals Saudi Arabia: A 2-year cross-sectional study from 2022 to 2024.

作者信息

Hassan Fadil, Jarwan Aseel, Alsubaey Abdullah, Bogari Mohammed, Aldawsari Abdullah, Alsabhi Faisal, Qusti Amin, Shahzad Muhammed

机构信息

Department of Surgery, King Saud Bin Abdulaziz University for Health and Sciences, Jeddah, Saudi Arabia.

Department of Surgery, KAMC Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.

出版信息

Urol Ann. 2025 Apr-Jun;17(2):112-119. doi: 10.4103/ua.ua_113_24. Epub 2025 Apr 17.

Abstract

INTRODUCTION

Chronic kidney disease is a global health challenge, often progressing to end-stage renal disease requiring renal replacement therapies such as dialysis or transplantation. Kidney transplantation is the preferred treatment due to its superior effectiveness in improving survival and quality of life compared to dialysis. In addition, living kidney donation, while generally safe, may impact the donor's psychological and social well-being. The present study investigates the quality of life and social outcomes of living kidney donors, offering important insights into donor experiences in Saudi Arabia.

METHODOLOGY

This cross-sectional study was conducted at King Abdulaziz Medical City, Riyadh, and Jeddah, Saudi Arabia, between 2022 and 2024. A total of 224 kidney donors participated, with data collected through telephone interviews using the validated Perceived Donation Consequences Scale to assess psychosocial outcomes, including physical health, quality of life, and social relationships. Demographic data were extracted from electronic medical records.

RESULTS

A total of 224 kidney donors participated in the study. The majority of donors were male (72.8%) and married (66.1%), with 79.9% donating to immediate family members. The study showed that 48.2% reported improved quality of life. Moreover, 90.2% of donors would choose to donate again, and 86.6% would recommend donation to others. While 75.4% of donors reported that the surgery met their expectations, 29% experienced ongoing physical symptoms such as pain and fatigue. Psychosocial outcomes were generally positive, with 78.6% reporting no negative impact on family relationships and 70.1% indicating that their job prospects were unaffected.

CONCLUSION

This study demonstrates that kidney donation generally leads to high levels of satisfaction and positive psychosocial outcomes for donors. While most donors reported improved quality of life and strong motivation to donate again, a subset experienced ongoing physical symptoms such as pain and fatigue.

摘要

引言

慢性肾脏病是一项全球性的健康挑战,常常会发展为终末期肾病,需要进行透析或移植等肾脏替代治疗。肾移植是首选治疗方法,因为与透析相比,它在提高生存率和生活质量方面效果更佳。此外,活体肾捐赠虽然总体安全,但可能会影响捐赠者的心理和社会福祉。本研究调查了活体肾捐赠者的生活质量和社会结局,为沙特阿拉伯捐赠者的经历提供了重要见解。

方法

这项横断面研究于2022年至2024年在沙特阿拉伯利雅得和吉达的阿卜杜勒阿齐兹国王医疗城进行。共有224名肾捐赠者参与,通过电话访谈收集数据,使用经过验证的感知捐赠后果量表评估心理社会结局,包括身体健康、生活质量和社会关系。人口统计学数据从电子病历中提取。

结果

共有224名肾捐赠者参与了该研究。大多数捐赠者为男性(72.8%)且已婚(66.1%),79.9%的捐赠者将肾捐给了直系亲属。研究表明,48.2%的捐赠者报告生活质量有所改善。此外,90.2%的捐赠者会选择再次捐赠,86.6%的捐赠者会向他人推荐捐赠。虽然75.4%的捐赠者表示手术符合他们的期望,但29%的捐赠者仍有疼痛和疲劳等持续的身体症状。心理社会结局总体呈积极态势,78.6%的捐赠者报告对家庭关系没有负面影响,70.1%的捐赠者表示其工作前景未受影响。

结论

本研究表明,肾捐赠总体上会给捐赠者带来较高的满意度和积极的心理社会结局。虽然大多数捐赠者报告生活质量有所改善且有强烈的再次捐赠意愿,但仍有一部分捐赠者存在疼痛和疲劳等持续的身体症状。

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Global Perspective on Kidney Transplantation: United States.肾脏移植的全球视角:美国
Kidney360. 2021 Aug 19;2(11):1836-1839. doi: 10.34067/KID.0002472021. eCollection 2021 Nov 25.
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Gender Disparities and Financial Barriers to Living Kidney Donation.活体肾捐赠中的性别差异与经济障碍。
J Am Soc Nephrol. 2018 Apr;29(4):1081-1083. doi: 10.1681/ASN.2018020158. Epub 2018 Mar 8.

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