Merdin Alparslan, Aydın Ümit
Süleyman Demirel University Faculty of Medicine, Department of Internal Medicine, Division Hematology, Isparta, Turkey.
Süleyman Demirel University Faculty of Medicine, Department of Internal Medicine, Isparta, Turkey.
Risk Manag Healthc Policy. 2025 Apr 21;18:1397-1405. doi: 10.2147/RMHP.S514701. eCollection 2025.
While hematopoietic stem cell transplantation is commonly associated with stem cell procedures in public discourse, "stem cell" remains a broad classification. More precise terminology such as "blood stem cell transplantation", "bone marrow transplantation", or "bone marrow stem cell transplantation" may better characterize hematopoietic stem cell procedures in both public and academic contexts. This study aimed to evaluate public comprehension of these specific terms and to assess awareness and attitudes toward stem cell donation, with particular focus on rural populations.
The study recruited 250 participants aged 19-60 years from rural Aksu District, Antalya Province. Individuals with a history of stem cell transplantation, those with a first-degree relative with a history of stem cell transplantation, and healthcare professionals were excluded from the study. The participants were asked 11 questions about their approach to stem cell donation and their thoughts on the subject.
Among the 250 participants, 51.6% (n=129) expressed willingness to become stem cell donors, whereas 48.4% (n=121) reported no willingness to be a donor. Interestingly, 95.6% (n=239) of the participants stated that they would like to know the identity of the person to whom they would be donating stem cells.
This study underscores the need to revisit current anonymity regulations in stem cell transplantation, particularly when both donor and recipient express a desire for mutual identification. Updating regulatory protocols and codes to facilitate information exchange in such cases might be better. Moreover, if the recipient may require further donations from the same donor, the donor should be consulted pre-transplantation about their willingness to provide further support. Their preferences should also be considered in the treatment approach when necessary.
在公众话语中,造血干细胞移植通常与干细胞程序相关联,但“干细胞”仍是一个宽泛的分类。更精确的术语,如“血液干细胞移植”“骨髓移植”或“骨髓干细胞移植”,在公众和学术背景下可能能更好地描述造血干细胞程序。本研究旨在评估公众对这些特定术语的理解,并评估对干细胞捐赠的认知和态度,特别关注农村人口。
该研究从安塔利亚省阿克苏地区农村招募了250名年龄在19至60岁之间的参与者。有干细胞移植史的个体、有一级亲属有干细胞移植史的个体以及医疗保健专业人员被排除在研究之外。参与者被问及11个关于他们对干细胞捐赠的态度以及对该主题的想法的问题。
在250名参与者中,51.6%(n = 129)表示愿意成为干细胞捐赠者,而48.4%(n = 121)报告不愿意成为捐赠者。有趣的是,95.6%(n = 239)的参与者表示他们想知道他们将向其捐赠干细胞的人的身份。
本研究强调有必要重新审视干细胞移植中当前的匿名规定,特别是当捐赠者和接受者都表示希望相互识别时。更新监管协议和准则以促进此类情况下的信息交流可能会更好。此外,如果接受者可能需要来自同一捐赠者的进一步捐赠,应在移植前咨询捐赠者是否愿意提供进一步支持。必要时,在治疗方法中也应考虑他们的偏好。