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拟似抗中性粒细胞胞浆抗体血管炎复发的粪类圆线虫感染

Strongyloides Stercoralis Infection Mimicking Relapse of ANCA Vasculitis.

作者信息

Meyyappan Jeyakumar, Prasad Narayan, Husain Shadab, Veeranki Vamsidhar, Patel Manas Ranjan, Kushwaha Ravi Shankar, Jha Gulab, Agrawal Vinita, Marak Rungmei

机构信息

Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, Uttar Pradesh, India.

Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, Uttar Pradesh, India.

出版信息

Indian J Nephrol. 2025 May-Jun;35(3):430-432. doi: 10.25259/IJN_23_2024. Epub 2024 Jul 1.

Abstract

A 48-year-old female with anti-neutrophilic cytoplasmic antibody (ANCA)-associated vasculitis, initially responded well to standard therapy but later presented with diffuse alveolar hemorrhage (DAH), simulating disease relapse. Following renal remission with standard immunosuppressive therapy, the patient exhibited fever, hemoptysis, and declining renal function, suggestive of a relapse. Bronchoscopy revealed DAH, raising concern for vasculitis exacerbation. However, discordant laboratory findings prompted scrutiny, leading to the detection of Strongyloides larvae in bronchoalveolar lavage.

摘要

一名48岁患有抗中性粒细胞胞浆抗体(ANCA)相关性血管炎的女性,最初对标准治疗反应良好,但后来出现弥漫性肺泡出血(DAH),类似疾病复发。在采用标准免疫抑制治疗实现肾脏缓解后,患者出现发热、咯血及肾功能下降,提示复发。支气管镜检查显示有弥漫性肺泡出血,引发了对血管炎加重的担忧。然而,不一致的实验室检查结果促使进一步检查,最终在支气管肺泡灌洗中发现了粪类圆线虫幼虫。

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