Najmanowicz Marta, Gajda Weronika, Nowatkowska Aleksandra, Kamiński Mikołaj, Cieluch Aleksandra, Sroczyńska Alicja, Kreczmer Anna, Michalak Magdalena, Adamska Anna, Frąckowiak Urszula, Michalski Mateusz, Araszkiewicz Aleksandra, Zozulińska-Ziółkiewicz Dorota, Gawrecki Andrzej
Department of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poland.
Department of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznan University of Medical Sciences, Poland.
Pediatr Endocrinol Diabetes Metab. 2025;31(1):1-8. doi: 10.5114/pedm.2025.148400.
Despite advances in therapy, most persons with type 1 diabetes (PwT1Ds) do not achieve treatment goals. Education is fundamental to the care of PwT1Ds treated with continuous subcutaneous insulin infusion (CSII).
To evaluate PwT1Ds treated with CSII and receiving in-hospital education and to identify factors associated with treatment effectiveness.
This cross-sectional study included adults with type 1 diabetes (T1D), who received diabetes education using the proprietary Structured Diabetes Education Program, GoPump, during "Insulin Pump Weeks" in 2022-2023. Metabolic control of diabetes was evaluated. Reports from personal insulin pumps, blood glucose meters, and continuous glucose monitoring (CGM) systems were assessed.
Data from 107 individuals with a median age of 26.7 years (Q1-Q3: 19.0-30.8) were analysed, including 65 women (60.7%). The median duration of T1D was 13 years (Q1-Q3: 10.0-18.0), and the median duration of personal insulin pump use was 8 years (Q1-Q3: 5.0-12.0). The median body mass index was 23.9 kg/m². CGM was used by 52.3% of individuals. The median time in range (TIR) was 57.0% (Q1-Q3: 45.0-69.5%), and the median glycated haemoglobin (HbA1c) level was 7.9% (Q1-Q3: 6.8-8.5%). A positive correlation was found between age and TIR (rs = 0.42, p = 0.001). The use of temporary basal rate and dual-wave and square bolus features was positively correlated with TIR (rs = 0.34, p = 0.012 and rs = 0.31, p = 0.021, respectively) and inversely with time above range > 250 mg/dl (rs = -0.37, p = 0.007 and rs = -0.27, p = 0.045, respectively). Lower HbA1c levels were observed in individuals with a higher number of daily boluses (rs = -0.33, p = 0.001).
In the study cohort, older age, more frequent use of advanced insulin pump features, and a higher number of daily boluses were associated with better glycaemic control in adults with T1D.
尽管治疗方法有所进步，但大多数1型糖尿病患者（PwT1Ds）仍未达到治疗目标。教育对于接受持续皮下胰岛素输注（CSII）治疗的PwT1Ds的护理至关重要。
评估接受CSII治疗并接受住院教育的PwT1Ds，并确定与治疗效果相关的因素。
这项横断面研究纳入了1型糖尿病（T1D）成人患者，他们在2022 - 2023年的“胰岛素泵周”期间使用专有的结构化糖尿病教育项目GoPump接受糖尿病教育。评估了糖尿病的代谢控制情况。对个人胰岛素泵、血糖仪和连续血糖监测（CGM）系统的报告进行了评估。
分析了107名个体的数据，中位年龄为26.7岁（第一四分位数 - 第三四分位数：19.0 - 30.8），其中包括65名女性（60.7%）。T1D的中位病程为13年（第一四分位数 - 第三四分位数：10.0 - 18.0），个人胰岛素泵使用的中位时长为8年（第一四分位数 - 第三四分位数：5.0 - 12.0）。中位体重指数为23.9kg/m²。52.3%的个体使用了CGM。中位血糖达标时间（TIR）为57.0%（第一四分位数 - 第三四分位数：45.0 - 69.5%），中位糖化血红蛋白（HbA1c）水平为7.9%（第一四分位数 - 第三四分位数：6.8 - 8.5%）。年龄与TIR之间存在正相关（rs = 0.42，p = 0.001）。临时基础率以及双波和方波大剂量注射功能的使用与TIR呈正相关（分别为rs = 0.34，p = 0.012和rs = 0.31，p = 0.021），与血糖高于250mg/dl的时间呈负相关（分别为rs = -0.37，p = 0.007和rs = -0.27，p = 0.045）。每日大剂量注射次数较多的个体HbA1c水平较低（rs = -0.33，p = 0.001）。
在该研究队列中，年龄较大、更频繁使用先进的胰岛素泵功能以及每日大剂量注射次数较多与T1D成人患者更好的血糖控制相关。
