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黑人先天性心脏病的模式与发病率

The pattern and frequency of congenital heart disease among blacks.

作者信息

van der Horst R L

出版信息

S Afr Med J. 1985 Sep 14;68(6):375-8.

PMID:4035509
Abstract

The types of cardiac malformations in 804 black patients of all ages in whom the diagnosis was confirmed by cardiac catheterization, surgery or autopsy are reported. The most frequent anomalies were ventricular septal defect, patent ductus arteriosus and tetralogy of Fallot. Among infants under 1 year of age, complete transposition of the great vessels accounted for the third-largest group of malformations. While pulmonary venous anomalies were extremely rare and hypoplastic left heart defects rare in the neonate, it is not considered that a racial predilection for differences in the frequency of various cardiac malformations exists. The frequency of coarctation of the aorta in the group as a whole was not lower than that found in studies among whites. Among black patients of all ages with heart disease (studied in a hospital environment) congenital cardiac malformations ranked as the second most common form of heart disease with a frequency of 26%. Among children aged 15 years or less, congenital heart disease ranked first with a frequency of 53%. It is suggested that a diagnosis of congenital heart disease is not made in the majority of blacks born with such malformations.

摘要

报告了804例各年龄段黑人患者经心导管检查、手术或尸检确诊的心脏畸形类型。最常见的异常是室间隔缺损、动脉导管未闭和法洛四联症。在1岁以下婴儿中,大动脉完全转位是第三大畸形类型。虽然肺静脉异常极为罕见,新生儿左心发育不全也很少见,但并不认为存在各种心脏畸形发生率差异的种族偏好。该组中主动脉缩窄的发生率并不低于白人研究中的发生率。在所有年龄段患有心脏病的黑人患者(在医院环境中研究)中,先天性心脏畸形是第二常见的心脏病形式,发生率为26%。在15岁及以下儿童中,先天性心脏病发生率为53%,位居第一。有人认为,大多数患有此类畸形的黑人出生时未被诊断出先天性心脏病。

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