Chen Xiang, Cheng Jing-Ping, Xu Ling-Ling, Chen Jia-Xin, Zhang Ying-Chun
Department of Gerontology, CR & WISCO General Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, Hubei Province, China.
Medical College, School of Medicine, Wuhan University of Science and Technology, Wuhan, Hubei Province, China.
Medicine (Baltimore). 2025 May 9;104(19):e42322. doi: 10.1097/MD.0000000000042322.
Fish gallbladder poisoning is an acute poisoning caused by eating fish gallbladders, which can damage the functions of multiple organs such as the heart, liver, and kidneys, and can be fatal in severe cases.
A 56-year-old female farmer, believing in a folk remedy, consumed the gallbladder of a black carp (Mylopharyngodon piceus) weighing approximately 4 kg to treat her cough. She subsequently developed abdominal pain and diarrhea for 6 days, followed by 1 day of anuria.
Fish gallbladder poisoning and multiple organ dysfunction syndrome.
The patient underwent oxygen therapy, anti-infective treatment, hepatoprotective measures, acid suppression and gastric protection, anti-heart failure management, correction of anemia, maintenance hemodialysis, and symptomatic and supportive care.
After nearly 2 weeks of hospitalization, the patient's condition improved. Following discharge, she continued maintenance hemodialysis for approximately 3 months, until her renal function was restored.
Fish gallbladder poisoning is primarily caused by toxins such as histamine, hydrocyanic acid, and cyprinol sulfate, leading to severe multiorgan dysfunction, particularly acute kidney injury. Early recognition, prompt hemodialysis, and comprehensive supportive treatment are essential for a favorable prognosis. Maintaining clinical vigilance and providing public health education on the dangers of consuming fish gallbladders are crucial for preventing similar incidents.
鱼胆中毒是因食用鱼胆而引起的急性中毒，可损害心脏、肝脏和肾脏等多个器官的功能，严重时可导致死亡。
一名56岁的女性农民，因相信民间偏方，食用了一条约4公斤重的青鱼的鱼胆来治疗咳嗽。随后她出现腹痛和腹泻6天，接着无尿1天。
鱼胆中毒和多器官功能障碍综合征。
患者接受了氧疗、抗感染治疗、保肝措施、抑酸和胃保护、抗心力衰竭治疗、纠正贫血、维持性血液透析以及对症和支持治疗。
经过近2周的住院治疗，患者病情好转。出院后，她继续进行了约3个月的维持性血液透析，直至肾功能恢复。
鱼胆中毒主要由组胺、氢氰酸和硫酸鲤醇等毒素引起，导致严重的多器官功能障碍，尤其是急性肾损伤。早期识别、及时进行血液透析和全面的支持治疗对于良好的预后至关重要。保持临床警惕并开展关于食用鱼胆危险性的公共卫生教育对于预防类似事件至关重要。
