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放射性食管炎的研究进展:一篇叙述性综述。

Research progress of radiation esophagitis: A narrative review.

作者信息

Wu Qiang, Li Qiuxia, Zhang Ruidan, Cui Yongbin, Zou Jingmin, Zhang Jianbo, Ma Changsheng, Han Dali, Peng Yiru

机构信息

Shandong Second Medical University, Weifang, Shandong Province, China.

Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China.

出版信息

Medicine (Baltimore). 2025 May 9;104(19):e42273. doi: 10.1097/MD.0000000000042273.

Abstract

Radiation esophagitis (RE) is an adverse reaction to radiotherapy for thoracic malignancies and a major factor limiting the dosage for thoracic tumors. In cases of RE, mild conditions may involve only discomfort in the throat, severe cases can present with intense pain and significant difficulty swallowing, and may lead to interruptions in radiation therapy, affecting the treatment outcome. However, much of the current research focuses on how to diagnose and treat the disease and needs to address the prevention of RE. In this review, several online databases, including PubMed, Web of Science, Google Scholar, the China National Knowledge Infrastructure, and the Chinese Medical Journal Database, were searched to collect relevant published studies. This review provides updated information on the pathogenesis, diagnosis, risk factors, development of predictive models, prevention, and treatment of RE, aiming to serve as a reference for its diagnosis, treatment, and prevention.

摘要

放射性食管炎(RE)是胸部恶性肿瘤放疗的一种不良反应,也是限制胸部肿瘤放疗剂量的主要因素。在放射性食管炎病例中,轻症可能仅表现为咽喉部不适,重症则会出现剧烈疼痛和明显吞咽困难,可能导致放疗中断,影响治疗效果。然而,目前的许多研究都集中在如何诊断和治疗该疾病,需要解决放射性食管炎的预防问题。在本综述中,检索了多个在线数据库,包括PubMed、Web of Science、谷歌学术、中国知网和中国生物医学文献数据库,以收集相关的已发表研究。本综述提供了关于放射性食管炎的发病机制、诊断、危险因素、预测模型的发展、预防和治疗的最新信息,旨在为其诊断、治疗和预防提供参考。

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Research progress of radiation esophagitis: A narrative review.放射性食管炎的研究进展:一篇叙述性综述。
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