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304例急性自发性蛛网膜下腔出血连续患者的总体结果。

Overall results in 304 consecutive patients with acute spontaneous subarachnoid hemorrhage.

作者信息

Testa C, Andreoli A, Arista A, Limoni P, Tognetti F

出版信息

Surg Neurol. 1985 Oct;24(4):377-85. doi: 10.1016/0090-3019(85)90294-0.

Abstract

The results obtained in 304 consecutive patients with spontaneous subarachnoid hemorrhage are described, the majority of whom (86%) were admitted while in acute condition. Only 46% of the patients in this series were in good condition at admission. The initial management was standardized for all patients, but the protocol of "delayed surgery" was applied to patients with subarachnoid hemorrhage from aneurysmal rupture. Two hundred and twenty-two patients (73%) had intracranial aneurysms. Of these, 20 (9%) were moribund and died shortly after admission; nine (4%) underwent emergency surgery due to the coexistence of a life-threatening cerebral hematoma; seven (3%) were operated upon within 3 days of admission; 78 (35%) died after rebleeding or after steady deterioration of the patient's condition due to vasospasm while awaiting surgery. Of the remaining 108 patients ready for delayed surgery, 12 (11%) (operation refused, elderly patients in poor general condition, spontaneous thrombosis of the aneurysm) were treated conservatively, and 96 (89%), who were in various clinical conditions, were actually operated on. Of these 96 patients, 79 (82%) exhibited excellent or good results, 5 (5%) were disabled, and 12 (12%) died. In the authors' experience, the overall management of intracranial aneurysms in unselected patients according to the protocol of delayed surgery results in significant loss of patients awaiting surgery, and good surgical results in the survivors.

摘要

本文描述了对304例连续的自发性蛛网膜下腔出血患者的治疗结果,其中大多数患者(86%)在急性期入院。本系列中只有46%的患者入院时状况良好。所有患者的初始治疗均标准化,但“延迟手术”方案应用于动脉瘤破裂所致蛛网膜下腔出血患者。222例患者(73%)患有颅内动脉瘤。其中,20例(9%)病情垂危,入院后不久死亡;9例(4%)因并存危及生命的脑血肿而接受急诊手术;7例(3%)在入院3天内接受手术;78例(35%)在再次出血或因血管痉挛导致病情持续恶化后死亡,这些患者在等待手术。在其余108例准备接受延迟手术的患者中,12例(11%)(拒绝手术、全身状况差的老年患者、动脉瘤自发血栓形成)接受保守治疗,96例(89%)处于不同临床状况,实际接受了手术。在这96例患者中,79例(82%)预后极佳或良好,5例(5%)致残,12例(12%)死亡。根据作者的经验,按照延迟手术方案对未经选择的患者进行颅内动脉瘤的整体治疗,会导致大量患者在等待手术过程中死亡,但幸存者的手术效果良好。

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