Qian Manfei, Wang Liyan, He Huihong, Tao Pengbo, Cai Linyu, Zhang Juying
Department of Interventional Medicine and Medical Oncology (II), Shaoxing People's Hospital, 312000 Shaoxing, Zhejiang, China.
Department of Geriatrics, Integrated Chinese and Western Medicine, Shaoxing People's Hospital, 312000 Shaoxing, Zhejiang, China.
Actas Esp Psiquiatr. 2025 May;53(3):557-569. doi: 10.62641/aep.v53i3.1788.
Surgery, as the preferred option to extend the survival of breast cancer patients, has increasingly garnered attention for its impact on patients' mental status and quality of life (QoL). Therefore, this study aimed to identify the factors affecting the QoL and mental status of breast cancer patients with schizophrenia, thus enabling subsequent interventions to improve their mental status and QoL.
This study included 125 breast cancer patients with schizophrenia, and their mental status and QoL were analyzed before and after surgery. The mental status of these patients was assessed using the Symptom Checklist-90 (SCL-90), and the World Health Organization Quality of Life-BREF (WHOQOL-BREF) was used to score their QoL. Baseline characteristics were recorded, including age, marital status, education level, and per capita monthly household income. The clinical and demographic data were statistically analyzed to identify factors affecting patients' mental status and QoL.
We observed that the mental status and QoL of breast cancer patients with schizophrenia at preoperative and postoperative stages were influenced by marital status, education level, tumor stage, tumor size, and monthly family income. Additionally, the type of surgery was significantly associated with postoperative mental status and QoL and was found to be a predictor influencing the overall QoL. Furthermore, surgery had a positive impact on patients across different treatment stages.
The psychological state and QoL of breast cancer patients with schizophrenia are influenced by various factors at different stages of treatment (preoperative and postoperative). Surgery significantly improves the patients' psychological state and QoL.
手术作为延长乳腺癌患者生存期的首选方案，其对患者心理状态和生活质量（QoL）的影响日益受到关注。因此，本研究旨在确定影响精神分裂症乳腺癌患者生活质量和心理状态的因素，从而进行后续干预以改善其心理状态和生活质量。
本研究纳入125例精神分裂症乳腺癌患者，分析其手术前后的心理状态和生活质量。使用症状自评量表90（SCL - 90）评估这些患者的心理状态，采用世界卫生组织生活质量简表（WHOQOL - BREF）对其生活质量进行评分。记录基线特征，包括年龄、婚姻状况、教育水平和家庭人均月收入。对临床和人口统计学数据进行统计分析，以确定影响患者心理状态和生活质量的因素。
我们观察到，精神分裂症乳腺癌患者术前和术后的心理状态和生活质量受婚姻状况、教育水平、肿瘤分期、肿瘤大小和家庭月收入的影响。此外，手术类型与术后心理状态和生活质量显著相关，并且是影响总体生活质量的一个预测因素。此外，手术对不同治疗阶段的患者均有积极影响。
精神分裂症乳腺癌患者的心理状态和生活质量在治疗的不同阶段（术前和术后）受多种因素影响。手术显著改善了患者的心理状态和生活质量。
