• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Potentiation of paclitaxel-induced apoptosis in a non-small cell lung cancer model using the traditional Chinese drug huaier: Network pharmacology analysis, experimental verification, and clinical impact.

作者信息

Zheng Wanrong, Lai Fobao

出版信息

Int J Clin Pharmacol Ther. 2025 Jul;63(7):349-352. doi: 10.5414/CP204745.

DOI:10.5414/CP204745
PMID:40356432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12188311/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1487/12188311/acc9caf3642f/intjclinpharmacol-63-349-01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1487/12188311/acc9caf3642f/intjclinpharmacol-63-349-01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1487/12188311/acc9caf3642f/intjclinpharmacol-63-349-01.jpg

相似文献

1
Potentiation of paclitaxel-induced apoptosis in a non-small cell lung cancer model using the traditional Chinese drug huaier: Network pharmacology analysis, experimental verification, and clinical impact.使用中药槐耳增强紫杉醇诱导的非小细胞肺癌模型中的细胞凋亡:网络药理学分析、实验验证及临床影响
Int J Clin Pharmacol Ther. 2025 Jul;63(7):349-352. doi: 10.5414/CP204745.
2
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of paclitaxel, docetaxel, gemcitabine and vinorelbine in non-small-cell lung cancer.对紫杉醇、多西他赛、吉西他滨和长春瑞滨在非小细胞肺癌中的临床疗效和成本效益进行的快速系统评价。
Health Technol Assess. 2001;5(32):1-195. doi: 10.3310/hta5320.
3
The Efficacy of Combined Use of Huaier Granules in the Treatment of Primary Liver Cancer: An Updated Systematic Review and Meta-Analysis.槐耳颗粒联合应用治疗原发性肝癌的疗效:一项更新的系统评价与Meta分析
Pharmaceuticals (Basel). 2025 Jun 13;18(6):884. doi: 10.3390/ph18060884.
4
Uncovering the anticancer effects of Bhallataka Taila in lung cancer: A metabolomic and network pharmacology approach.揭示毗黎勒油在肺癌中的抗癌作用:代谢组学和网络药理学方法
Bioimpacts. 2025 Apr 16;15:30568. doi: 10.34172/bi.30568. eCollection 2025.
5
YiQiChuTan formula (YQCTF) inhibit the progression of non-small cell lung cancer via down-regulating EGFR/ITGB2 signaling: Triangulated evidence from network pharmacology, proteomic profiling, and experimental validation.益气除痰方通过下调EGFR/ITGB2信号通路抑制非小细胞肺癌进展:来自网络药理学、蛋白质组学分析及实验验证的三角证据
Phytomedicine. 2025 Aug;144:156950. doi: 10.1016/j.phymed.2025.156950. Epub 2025 Jun 4.
6
Network Pharmacology Approach to Unveiling the Mechanism of Wolfberry Mulberry Raspberry Decoction in the Treatment of Sepsis-Induced Myocardial Dysfunction.基于网络药理学方法揭示枸杞桑椹覆盆子汤治疗脓毒症诱导的心肌功能障碍的机制
Drug Des Devel Ther. 2025 Jun 20;19:5293-5310. doi: 10.2147/DDDT.S502301. eCollection 2025.
7
Solidago decurrens Lour. Controls LPS-Induced Acute Lung Injury by Reducing Inflammatory Responses and Modulating the TLR4/NF-κB/NLRP3 Signaling Pathway.一枝黄花通过减轻炎症反应和调节TLR4/NF-κB/NLRP3信号通路来控制脂多糖诱导的急性肺损伤。
J Ethnopharmacol. 2025 Jun 17:120172. doi: 10.1016/j.jep.2025.120172.
8
Network pharmacology and molecular docking to elucidate the mechanism of antiaging of Platycodon grandiflorus.基于网络药理学和分子对接技术阐明桔梗抗衰老作用机制
Medicine (Baltimore). 2025 Jun 13;104(24):e42347. doi: 10.1097/MD.0000000000042347.
9
Integrated network pharmacology, transcriptomics, and experimental validation to explore the mechanism of Qihuang Jianpi Zishen granules against Sjögren's syndrome.整合网络药理学、转录组学和实验验证以探究芪黄健脾滋肾颗粒治疗干燥综合征的作用机制。
Sci Rep. 2025 Jul 1;15(1):21176. doi: 10.1038/s41598-025-03653-w.
10
Unraveling the Therapeutic Potential of Aiton in Myocardial Infarction: An Integrative Approach Combining Bioinformatics, Network Pharmacology, and Experimental Validation.揭示艾顿在心肌梗死中的治疗潜力:一种结合生物信息学、网络药理学和实验验证的综合方法。
Curr Pharm Des. 2025;31(18):1474-1497. doi: 10.2174/0113816128342405241204055321.

本文引用的文献

1
Temozolomide alleviates breast carcinoma via the inhibition of EGFR/ERK/ MMP-1 pathway with induction of apoptotic events.替莫唑胺通过抑制 EGFR/ERK/MMP-1 通路并诱导细胞凋亡来缓解乳腺癌。
Acta Cir Bras. 2024 May 24;39:e391624. doi: 10.1590/acb391624. eCollection 2024.
2
Network pharmacology study of the mechanism underlying the therapeutic effect of Zhujing pill and its main component oleanolic acid against diabetic retinopathy.基于网络药理学的竹节丸及其主要成分齐墩果酸治疗糖尿病视网膜病变作用机制研究。
Biosci Rep. 2023 Jan 31;43(1). doi: 10.1042/BSR20220893.
3
Rg3 regulates myocardial pyruvate metabolism via P300-mediated dihydrolipoamide dehydrogenase 2-hydroxyisobutyrylation in TAC-induced cardiac hypertrophy.
Rg3 通过 P300 介导的二氢硫辛酰胺脱氢酶 2-羟基异丁酰化调节 TAC 诱导的心肌丙酮酸代谢在心肌肥厚中的作用。
Cell Death Dis. 2022 Dec 26;13(12):1073. doi: 10.1038/s41419-022-05516-y.
4
The Anti-Constipation Effects of Raffino-Oligosaccharide on Gut Function in Mice Using Neurotransmitter Analyses, 16S rRNA Sequencing and Targeted Screening.利用神经递质分析、16S rRNA 测序和靶向筛选研究瑞鲍迪苷寡糖对小鼠肠道功能的抗便秘作用。
Molecules. 2022 Mar 30;27(7):2235. doi: 10.3390/molecules27072235.
5
HER3 Augmentation via Blockade of EGFR/AKT Signaling Enhances Anticancer Activity of HER3-Targeting Patritumab Deruxtecan in EGFR-Mutated Non-Small Cell Lung Cancer.阻断 EGFR/AKT 信号增强 HER3 靶向药物 patritumab deruxtecan 在 EGFR 突变型非小细胞肺癌中的抗肿瘤活性。
Clin Cancer Res. 2022 Jan 15;28(2):390-403. doi: 10.1158/1078-0432.CCR-21-3359. Epub 2021 Dec 17.
6
Multitarget Approaches against Multiresistant Superbugs.针对多重耐药超级细菌的多靶点方法。
ACS Infect Dis. 2020 Jun 12;6(6):1346-1365. doi: 10.1021/acsinfecdis.0c00001. Epub 2020 Mar 19.
7
Tropomodulin 3 modulates EGFR-PI3K-AKT signaling to drive hepatocellular carcinoma metastasis.Tropomodulin 3 通过调节 EGFR-PI3K-AKT 信号通路驱动肝癌转移。
Mol Carcinog. 2019 Oct;58(10):1897-1907. doi: 10.1002/mc.23083. Epub 2019 Jul 16.
8
Overcoming drug-resistant lung cancer by paclitaxel loaded tetrahedral DNA nanostructures.载紫杉醇的四面体 DNA 纳米结构克服耐药性肺癌。
Nanoscale. 2018 Mar 28;10(12):5457-5465. doi: 10.1039/c7nr09692e. Epub 2018 Feb 27.
9
Strong nuclear EGFR expression in colorectal carcinomas is associated with cyclin-D1 but not with gene EGFR amplification.结直肠癌中强核 EGFR 表达与 cyclin-D1 相关,但与基因 EGFR 扩增无关。
Diagn Pathol. 2011 Nov 3;6:108. doi: 10.1186/1746-1596-6-108.
10
Factors affecting bone marrow toxicity following administration of carboplatin and paclitaxel in patients with non-small cell lung cancer.非小细胞肺癌患者使用卡铂和紫杉醇后骨髓毒性的影响因素。
Anticancer Res. 2010 Apr;30(4):1365-9.