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心律失常中自主神经系统研究的发展与新趋势:一项2004年至2024年的文献计量学研究

The developments and emerging trends of Autonomic Nervous System Research in Arrhythmia: a bibliometric study from 2004 to 2024.

作者信息

Chen Tingting, Yang Yanfeng, Shi Kun, Si Feifei, Wen Yizhou, Yang Xiao

机构信息

Department of Pediatric Cardiology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

Department of Obstetrics, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.

出版信息

Front Neurosci. 2025 Apr 28;19:1595253. doi: 10.3389/fnins.2025.1595253. eCollection 2025.

Abstract

The role of the autonomic nervous system in cardiovascular diseases has increasingly attracted the attention of researchers. This study aims to review research on the autonomic nervous system in arrhythmias from 2004 to 2024, with a focus on understanding the development trends in this field. Data for this study were sourced from the Web of Science Core Collection. We constructed and analyzed bibliometric visualizations related to publication trends, countries/regions, institutions, journals, research categories, themes, references, and keywords. Over the past two decades, academic output related to the autonomic nervous system's role in arrhythmias has grown, although global research distribution remains uneven. The United States leads in publication volume and is home to many high-output institutions, providing it with significant academic influence and fostering international collaboration. By summarizing high-citation literature, clustering keywords, and performing a "burst detection" analysis of keywords, we identified that the mechanisms and assessment methods for autonomic nervous system regulation are major research focuses. Recent hotspots include the psychopathology related to the autonomic nervous system and autonomic regulation therapies. As the biomedical field shifts toward precision medicine, future research trends are likely to focus on identifying precise biomarkers for assessing autonomic nervous system function and developing novel strategies to regulate it. These strategies may include correcting immune dysfunction, psychological interventions, and surgical treatments. This study suggests that ganglionated plexi ablation may represent the most transformative intervention strategy for the Autonomic Nervous System currently available, and highlights electrodermal activity as an evaluation index with considerable potential for widespread application.

摘要

自主神经系统在心血管疾病中的作用日益受到研究人员的关注。本研究旨在回顾2004年至2024年期间关于心律失常中自主神经系统的研究,重点是了解该领域的发展趋势。本研究的数据来源于科学网核心合集。我们构建并分析了与发表趋势、国家/地区、机构、期刊、研究类别、主题、参考文献和关键词相关的文献计量可视化图表。在过去二十年中,与自主神经系统在心律失常中作用相关的学术产出有所增长,尽管全球研究分布仍不均衡。美国在发表量方面领先,拥有许多高产机构,具有重大的学术影响力并促进了国际合作。通过总结高被引文献、聚类关键词以及对关键词进行“突发检测”分析,我们确定自主神经系统调节的机制和评估方法是主要研究重点。近期热点包括与自主神经系统相关的精神病理学和自主调节疗法。随着生物医学领域向精准医学转变,未来的研究趋势可能集中在确定评估自主神经系统功能的精确生物标志物以及开发调节它的新策略。这些策略可能包括纠正免疫功能障碍、心理干预和手术治疗。本研究表明,节段性神经丛消融可能是目前可用的针对自主神经系统最具变革性的干预策略,并强调皮肤电活动作为一种具有广泛应用潜力的评估指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/074a/12066699/792ad0df3712/fnins-19-1595253-g001.jpg

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