Opayele Adewale V, Fagbamigbe Adeniyi F, Ochu Chinwe L, Ayebare Rodgers R, Faneye Adedayo O, Olaosebikan Adewemimo C, Falayi Oluwaseun E, Nwiyi Gloria O, Eziechina Sunday O, Uzoma Ikemefule R, Ibekwe Priscilla, Okonkwo Prosper, Shaweno Tamrat, Dereje Nebiyu, Nakasendwa Suzan, Muwonge Tonny, Fallah Mosoka P, Odaibo Georgina N
Department of Virology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Department of Epidemiology and Medical Statistics, Faculty of Public Health, University of Ibadan, Ibadan, Nigeria.
J Public Health Afr. 2025 Apr 28;16(1):685. doi: 10.4102/jphia.v16i1.685. eCollection 2025.
Vaccine hesitancy among healthcare workers (HCWs) hinders coronavirus disease 2019 (COVID-19) control efforts.
The aim of the study was to assess enhancers and barriers to the uptake of COVID-19 vaccine among HCWs in Ibadan, Nigeria.
Health facility-based cross-sectional study in Ibadan, a metropolitan city in Oyo state, Nigeria.
A questionnaire administered using REDCap assessed HCW vaccination status, attitudes and access using the Behavioural and Social drivers (BeSD) framework. Data analysis performed using STATA version 17 included descriptive statistics and modified Poisson regression.
Of the 1227 HCWs recruited, 82.8% received at least one dose. Vaccine uptake was higher among older HCWs compared to those below 25 years (45-54 years: prevalence ratio [PR] = 1.20, 95% confidence interval [CI]: 1.09, 1.33 and ≥ 55 years: PR = 1.17, 95% CI: 1.05, 1.30) and HCWs in private health centres (PR = 1.15, 95% CI: 1.08, 1.22). Most HCWs (83.5%) believed in vaccination for infectious diseases, but only 61.9% felt the same about COVID-19 vaccines. The major reasons for vaccine hesitancy among unvaccinated HCWs included the beliefs that vaccine development and authorisation were rushed (47 [26.1%]) and concerns about serious side effects (32 [17.8%]).
This study found that the uncertainty about COVID-19 vaccine safety is a key barrier to its uptake. Therefore, targeted education and communication strategies to improve vaccine confidence are crucial.
This study identifies why HCWs in Nigeria are hesitant about getting vaccinated. This information can help to improve vaccination rates in this group. It fits with the journal's focus on making African public health responses stronger.
医护人员对疫苗的犹豫阻碍了2019冠状病毒病（COVID-19）的防控工作。
本研究旨在评估尼日利亚伊巴丹医护人员接种COVID-19疫苗的促进因素和障碍。
在尼日利亚奥约州的大都市伊巴丹进行的基于卫生机构的横断面研究。
使用REDCap管理的问卷，采用行为和社会驱动因素（BeSD）框架评估医护人员的疫苗接种状况、态度和可及性。使用STATA 17版进行的数据分析包括描述性统计和修正泊松回归。
在招募的1227名医护人员中，82.8% 至少接种了一剂疫苗。与25岁以下的医护人员相比，年长的医护人员疫苗接种率更高（45-54岁：患病率比 [PR] = 1.20，95% 置信区间 [CI]：1.09, 1.33；≥ 55岁：PR = 1.17，95% CI：1.05, 1.30），私立卫生中心的医护人员也是如此（PR = 1.15，95% CI：1.08, 1.22）。大多数医护人员（83.5%）相信接种疫苗可预防传染病，但只有61.9% 的人对COVID-19疫苗持相同看法。未接种疫苗的医护人员对疫苗犹豫的主要原因包括认为疫苗研发和授权仓促（47 [26.1%]）以及担心严重副作用（32 [17.8%]）。
本研究发现，对COVID-19疫苗安全性的不确定性是其接种的关键障碍。因此，针对性的教育和沟通策略以提高疫苗信心至关重要。
本研究确定了尼日利亚医护人员对接种疫苗犹豫不决的原因。这些信息有助于提高该群体的疫苗接种率。它符合该期刊加强非洲公共卫生应对措施的重点。
