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射波刀与四维计算机断层扫描引导的立体定向体部放射治疗在肺癌治疗中的应用:病例报告

CyberKnife Versus Four-Dimensional Computed Tomography-Guided Stereotactic Body Radiation Therapy in the Treatment of Lung Cancer: A Case Report.

作者信息

Tang Lingrong, Yao Lei, Li Guang

机构信息

Department of Radiotherapy, The First Hospital of China Medical University, Shenyang, CHN.

出版信息

Cureus. 2025 Apr 12;17(4):e82138. doi: 10.7759/cureus.82138. eCollection 2025 Apr.

DOI:10.7759/cureus.82138
PMID:40357075
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12068358/
Abstract

Stereotactic body radiation therapy (SBRT) has emerged as a critical therapeutic option for treating lung and other solid tumors. Two prominent high-precision SBRT techniques currently in use are four-dimensional computed tomography-guided linear accelerator-based SBRT (4DCT-SBRT) and CyberKnife. This case presents a patient diagnosed with two distinct pulmonary lesions, each treated separately using 4DCT-SBRT and CyberKnife. By comparing target delineation, dose distribution, lesion response, and the capability to spare normal tissues, we evaluate the specific advantages of CyberKnife for particular clinical scenarios.

摘要

立体定向体部放射治疗(SBRT)已成为治疗肺癌和其他实体瘤的关键治疗选择。目前使用的两种突出的高精度SBRT技术是基于四维计算机断层扫描引导的直线加速器的SBRT(4DCT-SBRT)和射波刀。本病例介绍了一名被诊断患有两个不同肺部病变的患者,每个病变分别使用4DCT-SBRT和射波刀进行治疗。通过比较靶区勾画、剂量分布、病变反应以及保护正常组织的能力,我们评估了射波刀在特定临床场景中的具体优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd1f/12068358/b0e363d76763/cureus-0017-00000082138-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd1f/12068358/93395a11602a/cureus-0017-00000082138-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd1f/12068358/e9da99747f62/cureus-0017-00000082138-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd1f/12068358/b0e363d76763/cureus-0017-00000082138-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd1f/12068358/93395a11602a/cureus-0017-00000082138-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd1f/12068358/e9da99747f62/cureus-0017-00000082138-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd1f/12068358/b0e363d76763/cureus-0017-00000082138-i03.jpg

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本文引用的文献

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Synchronized Contrast-Enhanced 4DCT Simulation for Target Volume Delineation in Abdominal SBRT.用于腹部立体定向体部放疗中靶区勾画的同步对比增强4DCT模拟
Cancers (Basel). 2024 Dec 4;16(23):4066. doi: 10.3390/cancers16234066.
2
Dosimetric comparison of multiple SBRT delivery platforms for pancreatic cancer.多种胰腺癌 SBRT 治疗平台的剂量学比较。
Eur J Med Res. 2024 Nov 5;29(1):533. doi: 10.1186/s40001-024-02080-3.
3
Results of Stereotactic Body Radiotherapy With CyberKnife-M6 for Primary and Metastatic Lung Cancer.射波刀-M6立体定向体部放射治疗原发性和转移性肺癌的结果
World J Oncol. 2024 Aug;15(4):711-721. doi: 10.14740/wjon1865. Epub 2024 Jul 5.
4
Evaluation of computed tomography metal artifact and CyberKnife fiducial recognition for novel size fiducial markers.评估 CT 金属伪影和 CyberKnife 基准识别新型尺寸基准标记。
J Appl Clin Med Phys. 2023 Dec;24(12):e14142. doi: 10.1002/acm2.14142. Epub 2023 Sep 6.
5
Stereotactic Body Radiotherapy for the Management of Early-Stage Non-Small-Cell Lung Cancer: A Clinical Overview.立体定向体部放射治疗早期非小细胞肺癌的临床概述
JCO Oncol Pract. 2023 May;19(5):239-249. doi: 10.1200/OP.22.00475. Epub 2023 Feb 17.
6
SBRT focal dose intensification using an MR-Linac adaptive planning for intermediate-risk prostate cancer: An analysis of the dosimetric impact of intra-fractional organ changes.使用磁共振直线加速器自适应计划对中危前列腺癌进行立体定向体部放疗局部剂量强化:分次内器官变化的剂量学影响分析
Radiother Oncol. 2023 Feb;179:109441. doi: 10.1016/j.radonc.2022.109441. Epub 2022 Dec 19.
7
Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery.立体定向消融放疗治疗可手术的 I 期非小细胞肺癌(修订后的 STARS):一项单臂前瞻性试验的长期结果,与手术进行了预设比较。
Lancet Oncol. 2021 Oct;22(10):1448-1457. doi: 10.1016/S1470-2045(21)00401-0. Epub 2021 Sep 13.
8
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Sci Rep. 2021 Feb 18;11(1):4065. doi: 10.1038/s41598-021-83648-5.
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Med Dosim. 2020;45(4):346-351. doi: 10.1016/j.meddos.2020.04.004. Epub 2020 Jun 10.
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