Atia Gamal A, Abdal Dayem Ahmed, Taher Ehab S, Alghonemy Wafaa Y, Cho Ssang-Goo, Aldarmahi Ahmed A, Haque Md Azizul, Alshambky Abeer, Taymour Noha, Ibrahim Ateya M, Zaghamir Donia E, Elmorsy Ekramy M, Hetta Helal F, Mohamed Mohamed E, Abass Kasim S, Khanday Shifan, Abdeen Ahmed
Department of Oral Medicine, Periodontology, and Diagnosis, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt.
Department of Stem Cell and Regenerative Biotechnology, School of Advanced Biotechnology, Molecular & Cellular Reprogramming Center, Institute of Advanced Regenerative Science, and Institute of Health, Aging & Society, Konkuk University, Seoul, Republic of Korea.
Front Bioeng Biotechnol. 2025 Apr 28;13:1571066. doi: 10.3389/fbioe.2025.1571066. eCollection 2025.
Urine-based therapy, an ancient practice, has been utilized across numerous civilizations to address a wide range of ailments. Urine was considered a priceless resource in numerous traditional therapeutic applications due to its reported medicinal capabilities. While the utilization of urine treatment is contentious and lacks significant support from modern healthcare, the discovery of urine-derived stem cells (UDSCs) has introduced a promising avenue for cell-based therapy. UDSCs offer a noninvasive and easily repeatable collection method, making them a practical and viable option for therapeutic applications. Research has shown that UDSCs contribute to organ preservation by promoting revascularization and decreasing inflammatory reactions in many diseases and conditions. This review will outline the contemporary status of UDSCs research and explore their potential applications in both fundamental science and medical practice.
基于尿液的疗法是一种古老的疗法，在众多文明中都有应用，用于治疗各种疾病。在许多传统治疗应用中，尿液因其据称的药用能力而被视为一种宝贵资源。虽然尿液治疗的应用存在争议，且缺乏现代医疗保健的大力支持，但尿液衍生干细胞（UDSCs）的发现为基于细胞的治疗开辟了一条充满希望的途径。UDSCs提供了一种非侵入性且易于重复的采集方法，使其成为治疗应用中切实可行的选择。研究表明，在许多疾病和病症中，UDSCs通过促进血管再生和减少炎症反应，有助于器官保存。本综述将概述UDSCs研究的现状，并探讨它们在基础科学和医学实践中的潜在应用。
