Arafat Yousef, Boms Stefanie, Kautz Ocko, von Stemm Andrea, Gambichler Thilo
Klinik für Dermatologie, Christliches Klinikum Unna, Obere Husemannstr. 2, 59423, Unna, Deutschland.
MVZ Dermatologie & Histologie Westerstede, 26655, Westerstede, Deutschland.
Dermatologie (Heidelb). 2025 Jul;76(7):442-444. doi: 10.1007/s00105-025-05499-9. Epub 2025 May 13.
We report on a woman with palmoplantar whitish-yellowish aggregated, partly ulcerated papules on a slightly erythematous base. Histological examination showed pale amorphous nodular deposits in the dermis. On radiological examination, calcifications could be ruled out. Laboratory tests showed marked hyperuricemia and chronic renal insufficiency. We diagnosed miliary gout (MG) and initiated uric acid-reducing therapy with allopurinol 100 mg/day. First described in 2007, MG presenting with multiple whitish-yellowish papules is a rare intradermal variant of classic gout that is characterized by subcutaneous deposits. Clinically, MG can be confused with other dermatoses, for example, cutaneous calcification or pustular palmoplantar psoriasis.
我们报告了一名女性患者，其手掌和足底有灰白色至淡黄色聚集性丘疹，部分丘疹有溃疡，基底略呈红斑状。组织学检查显示真皮内有苍白无定形结节状沉积物。影像学检查排除了钙化。实验室检查显示明显的高尿酸血症和慢性肾功能不全。我们诊断为粟粒性痛风（MG），并开始使用100毫克/天的别嘌醇进行降尿酸治疗。MG于2007年首次被描述，表现为多个灰白色至淡黄色丘疹，是经典痛风的一种罕见的真皮内变体，其特征为皮下沉积物。临床上，MG可能会与其他皮肤病混淆，例如皮肤钙化或脓疱性掌跖银屑病。
