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[短肠综合征实用指南]

[Practical guideline for short bowel syndrome].

作者信息

Dabsch Stefanie, Datz Christian, Dejaco Clemens, Harpain Felix, Hütterer Elisabeth, Kramer Ludwig, Loschko Nina, Moschen Alexander, Stift Anton, Vogelsang Harald

机构信息

Klinische Abteilung für Gastroenterologie und Hepatologie, Universitätsklinik für Innere Medizin 3, Medizinische Universität Wien, Vienna, Austria.

Abteilung für Innere Medizin, Krankenhaus Oberndorf, Lehrkrankenhaus der Paracelsus Medizinischen Privatuniversität Salzburg, Salzburg, Austria.

出版信息

Z Gastroenterol. 2025 May;63(5):502-511. doi: 10.1055/a-2375-4601. Epub 2025 May 13.

Abstract

Short bowel syndrome is a rare complex disease that mainly develops due to extensive bowel resections and can lead to chronic intestinal failure. Due to the decreased intestinal surface absorption of macronutrient, micronutrient and/or fluids is reduced. Correspondingly manifold symptoms arise as diarrhoea, weight loss, vitamin deficiencies, chronic kidney disease, hepatopathy and others with great impact on quality of life of patients. Therapy is complex and needs interdisciplinary collaboration between dieticians, gastroenterologists, surgeons and also a dense monitoring of general practitioners. Commonly patients need permanent home-parenteral support. Therapies have to be decided individually and have to be reviewed regularly for effectivity and side effects. Furthermore, periodic monitoring of several clinical and laboratory tests should be performed. Morbidity and mortality of this disease complex is high and lead by appearance and management of complications. This practical guide should give an overview about the disease, diagnostics and management and should enable the best possible care of these complex patients.

摘要

短肠综合征是一种罕见的复杂疾病,主要因广泛的肠道切除而发生,并可导致慢性肠衰竭。由于肠道对大量营养素、微量营养素和/或液体的表面吸收减少,相应地会出现多种症状,如腹泻、体重减轻、维生素缺乏、慢性肾病、肝病等,对患者的生活质量有很大影响。治疗很复杂,需要营养师、胃肠病学家、外科医生之间进行跨学科协作,全科医生也需要密切监测。通常患者需要长期的家庭肠外支持。治疗必须个体化决定,并且必须定期检查其有效性和副作用。此外,应定期进行多项临床和实验室检查。这种复杂疾病的发病率和死亡率很高,主要由并发症的出现和处理所致。本实用指南应概述该疾病、诊断和管理方法,并应使这些复杂患者能够得到尽可能好的护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/664f/12074862/b9f5c7cf68a3/10-1055-a-2375-4601_25522477.jpg

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