Park You-Rim, Eom Joo Beom
Department of Biomedical Science, College of Medicine, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan, 31116, Korea.
Sci Rep. 2025 May 13;15(1):16586. doi: 10.1038/s41598-025-01707-7.
We report a non-contact burn severity assessment system using the image-based photoplethysmography (IPPG) technique by fabricating a multi-wavelength imaging system. In this burn assessment system, four wavelengths (visible light wavelengths of 405 nm, 520 nm, 660 nm, and near-infrared wavelength of 940 nm) were used, and burn severity was identified based on the fact that each wavelength has different penetration depths. Each wavelength was set to irradiate with the same optical power (1 mW/cm²), and IPPG was acquired using images captured at 35 frames per second for wavelengths with different penetration depths. To measure burn severity, we created burn lesion models using hairless mice. For each degree of burn, we acquired images of the burn area at four different wavelengths, measured IPPG from the acquired images, and observed the signal change at each wavelength to evaluate burn severity. In addition, while monitoring the healing process, we observed that IPPG recovered as the blood flow in the tissue normalized. Through the results of this study, we expect that IPPG technology will be used not only as a non-contact technology to evaluate burn severity, but also as a new method to monitor the burn recovery process in real time.
我们报告了一种通过制造多波长成像系统，使用基于图像的光电容积脉搏波描记术（IPPG）技术的非接触式烧伤严重程度评估系统。在这个烧伤评估系统中，使用了四个波长（405纳米、520纳米的可见光波长、660纳米和940纳米的近红外波长），并且基于每个波长具有不同穿透深度这一事实来识别烧伤严重程度。每个波长设置为以相同的光功率（1毫瓦/平方厘米）进行照射，并使用以每秒35帧捕获的不同穿透深度波长的图像来采集IPPG。为了测量烧伤严重程度，我们使用无毛小鼠创建了烧伤损伤模型。对于每个烧伤程度，我们在四个不同波长下采集烧伤区域的图像，从采集的图像中测量IPPG，并观察每个波长处的信号变化以评估烧伤严重程度。此外，在监测愈合过程时，我们观察到随着组织中的血流恢复正常，IPPG也恢复了。通过这项研究的结果，我们期望IPPG技术不仅将用作评估烧伤严重程度的非接触技术，而且还将作为实时监测烧伤恢复过程的新方法。
