Rashid Md Mahbubur, Hu Nan, Khan Jahidur Rahman, Chan Mei, Gray Melinda, Owens Louisa, Jaffe Adam, Homaira Nusrat
School of Clinical Medicine, Faculty of Medicine, UNSW Sydney, Sydney, New South Wales, Australia.
Respiratory Department, Sydney Children's Hospital Randwick, Sydney, New South Wales, Australia.
Respirology. 2025 Sep;30(9):871-881. doi: 10.1111/resp.70049. Epub 2025 May 13.
Worldwide, up to 40% of all asthma hospitalisations are due to repeat admissions. This study aimed to estimate the burden of asthma readmission among children aged 2 to 17 years in New South Wales (NSW), Australia.
A retrospective longitudinal whole-of-population-based cohort study was conducted using linked administrative data. Children born in NSW from 2005 to 2015 having at least one asthma hospitalisation after the age of 2 years were included in the study and followed up for 12 months from the asthma index hospitalisation. The incidence rates for asthma first readmission within 12 months and associated direct medical costs were calculated.
During 2007-2022, 48,217 asthma hospitalisations occurred in children, with 28,177 children hospitalised for asthma as a primary diagnosis identified as asthma index hospitalisations. Among them, 21.6% experienced first asthma readmissions within 12 months, including over 80% from the 2-4 years age group and a significant proportion from socioeconomically disadvantaged areas. The overall incidence rate of first asthma readmission was 23.8 per 100 person-years and 28.7 per 100 person-years for children aged 2-4 years. The highest incidence rate (38.3 per 1000 person-months) occurred within 1 month. The total direct medical cost of the first asthma readmission within 12 months was AU$ 15.6 million.
Our study suggests that pre-school children have the highest rate of asthma readmission, with a significant economic burden highlighting the need for identifying modifiable factors such as asthma management after discharge to reduce the burden of asthma hospital readmission in children.
在全球范围内,高达40%的哮喘住院病例是由于再次入院。本研究旨在评估澳大利亚新南威尔士州(NSW)2至17岁儿童哮喘再入院的负担。
利用关联的行政数据进行了一项基于全人群的回顾性纵向队列研究。纳入2005年至2015年在新南威尔士州出生、2岁后至少有一次哮喘住院记录的儿童,并从哮喘索引住院起随访12个月。计算了12个月内哮喘首次再入院的发病率及相关直接医疗费用。
在2007年至2022年期间,儿童共发生48217例哮喘住院病例,其中28177例以哮喘为主要诊断的住院病例被确定为哮喘索引住院病例。其中,21.6%的患儿在12个月内经历了首次哮喘再入院,其中超过80%来自2至4岁年龄组,且很大一部分来自社会经济弱势地区。2至4岁儿童首次哮喘再入院的总体发病率为每100人年23.8例,每100人年28.7例。最高发病率(每1000人月38.3例)出现在1个月内。12个月内首次哮喘再入院的总直接医疗费用为1560万澳元。
我们的研究表明,学龄前儿童哮喘再入院率最高,经济负担较重,这凸显了识别可改变因素(如出院后哮喘管理)以减轻儿童哮喘住院再入院负担的必要性。