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小肠肿瘤:在一家三级护理医院进行的为期7年的研究。

Small Bowel Tumors: A 7-Year Study in a Tertiary Care Hospital.

作者信息

Cazacu Sergiu Marian, Cârțu Dan, Popescu Mihai, Streba Liliana, Ungureanu Bogdan Silviu, Iovănescu Vlad Florin, Cimpoeru Mihai, Mirea Cecil Sorin, Surlin Valeriu Marian, Mogoantă Stelian, Florescu Mirela Marinela

机构信息

Gastroenterology Department, University of Medicine and Pharmacy, 200349 Craiova, Romania.

Surgery Department, University of Medicine and Pharmacy, 200349 Craiova, Romania.

出版信息

Cancers (Basel). 2025 Apr 27;17(9):1465. doi: 10.3390/cancers17091465.

Abstract

(1) Background: Tumors of the small bowel represent 3-6% of gastrointestinal neoplasms and 3-6% of GI malignancies. The difficulties regarding the diagnosis are associated with larger tumors at the moment of the diagnosis and with advanced forms of malignant tumors, associated with a dismal prognosis. (2) Methods: We performed an observational, retrospective, cohort study that included patients with small bowel tumors admitted to the Craiova County Emergency Clinic Hospital between 1 January 2017 and 31 December 2023. The data were collected from the analysis of the patient's discharge documents from the Hippocrates computer system of the hospital and the evaluation of endoscopy databases. Patients under 16 years of age, those with no pathological confirmation of the malignancy, and those with insufficient data were excluded. (3) Results: A total of 80 cases of small bowel tumors were diagnosed; 72.5% were malignant, of which 10.3% were metastases. The most frequent primary malignant small bowel tumor was adenocarcinoma; two squamous cell carcinomas were noted. CT scans and upper digestive endoscopy represent the most frequent imaging methods for the diagnosis. The prognosis for malignant tumors was poor, with a 41% 5-year survival rate. (4) Conclusions: Small bowel tumors are rarely encountered, with 72.5% being malignant, and were diagnosed at large dimensions and in advanced stages for malignant tumors, with a dismal prognosis.

摘要

(1) 背景:小肠肿瘤占胃肠道肿瘤的3 - 6%,占胃肠道恶性肿瘤的3 - 6%。诊断方面的困难与诊断时肿瘤较大以及恶性肿瘤的晚期形式有关,预后不佳。(2) 方法:我们进行了一项观察性、回顾性队列研究,纳入了2017年1月1日至2023年12月31日期间入住克拉约瓦县急诊临床医院的小肠肿瘤患者。数据收集自对医院希波克拉底计算机系统中患者出院文件的分析以及内镜数据库的评估。排除16岁以下患者、无恶性肿瘤病理确诊患者以及数据不足的患者。(3) 结果:共诊断出80例小肠肿瘤;72.5%为恶性,其中10.3%为转移瘤。最常见的原发性恶性小肠肿瘤是腺癌;发现了2例鳞状细胞癌。CT扫描和上消化道内镜检查是最常用的诊断成像方法。恶性肿瘤的预后较差,5年生存率为41%。(4) 结论:小肠肿瘤很少见,72.5%为恶性,且恶性肿瘤在诊断时体积较大且处于晚期,预后不佳。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e51/12071178/49d203eee9f3/cancers-17-01465-g001.jpg

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