Masselli Gabriele, Di Bella Chiara
Department of Radiological Sciences, Oncology and Pathology, Policlinico Umberto I, Sapienza University of Rome, 00161 Rome, Italy.
Diagnostics (Basel). 2025 Apr 23;15(9):1070. doi: 10.3390/diagnostics15091070.
The combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) is a modern, highly advanced diagnostic tool that offers numerous advantages in the treatment and management of some pediatric pathologies. The use of PET/MR in children provides high-resolution images with outstanding tissue characterization, as well as important metabolic and physiological information; it is not only essential for early diagnosis, but also for the assessment and management of oncological, neurological, and cardiovascular diseases. The hybrid PET/MR is a multimodal approach that reduces the need for separate examinations, minimizes radiation exposure, and improves the overall experience for pediatric patients. In addition, PET/MR, by combining functional data, allows for more precise therapeutic planning and monitoring of treatment responses, optimizing clinical interventions especially with regard to staging and follow-up. This review will explore the benefits, weaknesses, and emerging applications of PET/MR in pediatric patients.
正电子发射断层扫描（PET）与磁共振成像（MRI）相结合是一种现代的、高度先进的诊断工具，在某些儿科疾病的治疗和管理中具有诸多优势。在儿童中使用PET/MR可提供具有出色组织特征的高分辨率图像，以及重要的代谢和生理信息；它不仅对早期诊断至关重要，而且对肿瘤、神经和心血管疾病的评估和管理也很重要。混合型PET/MR是一种多模态方法，可减少单独检查的需求，将辐射暴露降至最低，并改善儿科患者的整体体验。此外，PET/MR通过结合功能数据，能够进行更精确的治疗规划和治疗反应监测，尤其在分期和随访方面优化临床干预。本综述将探讨PET/MR在儿科患者中的益处、缺点及新兴应用。
