Sawang Jessica, Numbers Katya, Lam Ben C P, Reppermund Simone
Centre for Healthy Brain Ageing, Discipline of Psychiatry & Mental Health, Faculty of Medicine & Health, University of New South Wales (UNSW), Sydney 2052, Australia.
School of Psychology and Public Health, La Trobe University, Melbourne 3086, Australia.
Diagnostics (Basel). 2025 Apr 30;15(9):1145. doi: 10.3390/diagnostics15091145.
: Negative attitudes towards ageing, depressive symptoms, and impairment in instrumental activities of daily living (IADL) are associated with worse health outcomes in older adults, including increased risk of dementia. Little is known about the longitudinal impact of depressive symptoms and functional impairment on ageing attitudes in older people. Identifying the relationships between these risk factors may help inform interventions targeting early dementia. The aim of this study was to determine whether depressive symptoms and functional impairment are associated with ageing attitudes over 6 years. : Participants included 172 community-dwelling adults aged 76-96 years without dementia from the Sydney Memory and Ageing Study who were followed up over 6 years. Multiple linear regression models were used to examine prospective relationships between depressive symptoms, IADL (informant-reported or performance-based) and ageing attitudes. : After adjusting for potential confounding variables, more baseline depressive symptoms were associated with more negative ageing attitudes towards physical change (B = -0.10, 95%CI -0.18 to -0.02, = 0.021) and psychological growth (B = -0.09, 95%CI -0.17 to -0.01, = 0.037), and worse informant-reported IADL was associated with more negative ageing attitudes towards psychosocial change (B = -0.36, 95%CI -0.64 to -0.09, = 0.010) over 6 years. : The results highlight the importance of assessing and treating depressive symptoms and functional decline in older people, as they are significantly associated with negative attitudes about the ageing process, a known risk factor of worse health outcomes, including dementia.
对衰老的消极态度、抑郁症状以及日常生活工具性活动（IADL）受损与老年人更差的健康结局相关，包括患痴呆症的风险增加。关于抑郁症状和功能障碍对老年人衰老态度的纵向影响知之甚少。确定这些风险因素之间的关系可能有助于为针对早期痴呆症的干预措施提供信息。本研究的目的是确定抑郁症状和功能障碍是否与6年期间的衰老态度相关。：参与者包括来自悉尼记忆与衰老研究的172名年龄在76 - 96岁之间、无痴呆症的社区居住成年人，他们接受了6年的随访。使用多元线性回归模型来检验抑郁症状、IADL（由 informant 报告或基于表现）与衰老态度之间的前瞻性关系。：在调整潜在的混杂变量后，更多的基线抑郁症状与对身体变化的更消极衰老态度相关（B = -0.10，95%CI -0.18至 -0.02，P = 0.021）以及心理成长（B = -0.09，95%CI -0.17至 -0.01，P = 0.037），并且更差的 informant 报告的IADL与6年期间对心理社会变化的更消极衰老态度相关（B = -0.36，95%CI -0.64至 -0.09，P = 0.010）。：结果强调了评估和治疗老年人抑郁症状和功能衰退的重要性，因为它们与对衰老过程的消极态度显著相关，而消极态度是包括痴呆症在内的更差健康结局的已知风险因素。
