Strasding Malin, Sailer Irena, Merino-Higuera Elizabeth, Zarauz Cristina, Pitta Joao, Latyshev Andrei, Wittmann Udo, Nesic Dobrila
Division of Fixed Prosthodontics and Biomaterials, University Clinic of Dental Medicine, University of Geneva, Rue Michel-Servet 1, CH-1211 Geneva, Switzerland.
Center of Dental Medicine, Division of Periodontology and Peri-Implant Diseases, Clinic of Conservative and Preventive Dentistry, University of Zurich, Plattenstrasse 11, CH-8032 Zurich, Switzerland.
Materials (Basel). 2025 Apr 25;18(9):1951. doi: 10.3390/ma18091951.
Tooth loss results in hard- and soft-tissue volume loss over time. We compared the handling of three different soft tissue substitutes (STS) to the subepithelial connective tissue graft (SCTG) for soft tissue volume augmentation in a pig ex vivo model.
Five dentists simultaneously shaped, placed and sutured randomized four graft types in single-tooth soft tissue defects created in pig mandibles. The STS, produced from slightly crosslinked collagen fibres (VCMX), were either 3 mm or 6 mm thick blocks or a newly developed pre-customized saddle-shape. Each graft type was handled 20 times. The time required for shaping, placement, and suturing was recorded. Dentists reported outcomes on the grafts' handling were evaluated with a visual-analogue-scale (VAS). Statistical analysis included calculating means and medians and testing significance.
The mean time of 0.72 min for shaping the pre-customized saddle-shape STS was significantly lower than 1.31 min for SCTG, 1.73 min for 3 mm STS and 2.17 min for 6 mm STS. Placement/suturing time was similar for all grafts. The dentists mainly preferred the saddle-shape STS and the SCTG.
The saddle-shape STS required less time for graft-shaping and, therefore, reduced the overall treatment time, suggesting a more efficient and less invasive workflow for soft tissue augmentation.
随着时间推移，牙齿缺失会导致软硬组织体积减少。在猪离体模型中，我们比较了三种不同软组织替代物（STS）与上皮下结缔组织移植（SCTG）在软组织体积增加方面的操作情况。
五名牙医同时对猪下颌骨上单颗牙齿软组织缺损处随机放置的四种移植物进行塑形、放置和缝合。由轻度交联胶原纤维制成的STS（VCMX）为3毫米或6毫米厚的块状物或新开发的预先定制的鞍形物。每种移植物类型操作20次。记录塑形、放置和缝合所需时间。用视觉模拟量表（VAS）评估牙医报告的移植物操作结果。统计分析包括计算均值和中位数并检验显著性。
预先定制的鞍形STS塑形平均时间为0.72分钟，显著低于SCTG的1.31分钟、3毫米厚STS的1.73分钟和6毫米厚STS的2.17分钟。所有移植物的放置/缝合时间相似。牙医主要偏好鞍形STS和SCTG。
鞍形STS在移植物塑形方面所需时间更少，因此减少了总体治疗时间，表明软组织增加的工作流程更高效且侵入性更小。
