Kurowiak Jagoda, Piesik Krystian, Klekiel Tomasz
Department of Biomedical Engineering, Institute of Material and Biomedical Engineering, Faculty of Engineering and Technology, University of Zielona Gora, Licealna 9 Street, 65-417 Zielona Gora, Poland.
Collegium Medicum, University of Zielona Gora, Licealna 9 Street, 65-417 Zielona Góra, Poland.
Materials (Basel). 2025 Apr 29;18(9):2021. doi: 10.3390/ma18092021.
In this article, an analysis of the problem of treating bone defects using cranial bone disorders as an example is presented. The study was performed in the context of the development of various implant biomaterials used to fill bone defects. An analysis of the requirements for modern materials is undertaken, indicating the need for their further development. The article focuses particular attention on these biomaterial properties, which have an influence on bioresorbability and promote osteointegration and bone growth. The analysis showed the need for further development of biomaterials, the characteristics of which may be multifunctionality. Multifunctional scaffolds are those that simultaneously fill and stabilize the defect and contribute to the proper process of regeneration and reconstruction of cranial bones. Due to the complex structure of the skull and special protective functions, there is a need to develop innovative implants. Implants with complex geometries can be successfully manufactured using additive technologies.
本文以颅骨疾病为例，对骨缺损治疗问题进行了分析。该研究是在用于填充骨缺损的各种植入生物材料的发展背景下进行的。对现代材料的要求进行了分析，表明有必要对其进行进一步开发。本文特别关注这些生物材料的特性，这些特性会影响生物可吸收性并促进骨整合和骨生长。分析表明需要进一步开发生物材料，其特性可能是多功能性。多功能支架是那些能够同时填充和稳定缺损并有助于颅骨再生和重建的正常过程的支架。由于颅骨结构复杂且具有特殊的保护功能，因此需要开发创新的植入物。具有复杂几何形状的植入物可以使用增材制造技术成功制造。
