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踝关节骨关节炎患者全踝关节置换术与踝关节融合术的早期疗效及并发症比较:大数据分析

Comparing Early Outcomes and Complications Between Total Ankle Arthroplasty and Ankle Arthrodesis in Patients with Ankle Osteoarthritis: Big Data Analysis.

作者信息

Mahamid Assil, Laver Lior, Maman David, Abu Elhija Amir, Haj Yahya Mohammad, Haverkamp Daniel, Berkovich Yaron, Behrbalk Eyal

机构信息

Department of Orthopedics, Hillel Yaffe Medical Center, Hadera 3810101, Israel.

Rappaport Faculty of Medicine, Technion University Hospital (Israel Institute of Technology), Haifa 3200003, Israel.

出版信息

J Clin Med. 2025 Apr 23;14(9):2909. doi: 10.3390/jcm14092909.

DOI:10.3390/jcm14092909
PMID:40363940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12072959/
Abstract

End-stage ankle osteoarthritis (OA) severely limits function and quality of life. Total ankle arthroplasty (TAA) and ankle arthrodesis (AA) are key surgical interventions when conservative treatment fails. This study compares TAA and AA outcomes using a national dataset to inform patient-centered care. A retrospective analysis of 27,595 patients undergoing TAA or AA from 2016-2019 was conducted using the National Inpatient Sample. Propensity score matching addressed baseline differences. Primary OA was more prevalent in TAA (85.9%) than in AA (55.4%). TAA utilization rose from 73% to 78% ( < 0.0001), while AA declined. TAA patients were older (65.6 vs. 59.7 years), more often Medicare-insured, and predominantly Caucasian. AA patients had higher rates of comorbidities, including diabetes, obesity, lung disease, and mental disorders (all < 0.0001). TAA and AA cater to distinct patient profiles. TAA is increasingly favored and associated with lower immediate risks, though procedure choice should be individualized based on comorbidities and risk profiles. These insights support evidence-based decision-making in end-stage ankle OA management.

摘要

终末期踝关节骨关节炎(OA)严重限制了功能和生活质量。当保守治疗失败时,全踝关节置换术(TAA)和踝关节融合术(AA)是关键的手术干预措施。本研究使用全国数据集比较TAA和AA的治疗效果,以为以患者为中心的护理提供参考。利用全国住院患者样本对2016年至2019年期间接受TAA或AA治疗的27595例患者进行了回顾性分析。倾向评分匹配解决了基线差异问题。原发性OA在TAA组(85.9%)比在AA组(55.4%)中更为普遍。TAA的使用率从73%上升至78%(<0.0001),而AA的使用率则有所下降。TAA患者年龄更大(65.6岁对59.7岁),更多人有医疗保险,且主要为白种人。AA患者的合并症发生率更高,包括糖尿病、肥胖、肺部疾病和精神障碍(均<0.0001)。TAA和AA针对不同的患者群体。TAA越来越受到青睐,且与之相关的直接风险较低,不过手术选择应根据合并症和风险状况进行个体化。这些见解为终末期踝关节OA的管理提供了循证决策依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76e2/12072959/c9a899e3cc8e/jcm-14-02909-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76e2/12072959/dba398fd887e/jcm-14-02909-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76e2/12072959/c9a899e3cc8e/jcm-14-02909-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76e2/12072959/dba398fd887e/jcm-14-02909-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76e2/12072959/c9a899e3cc8e/jcm-14-02909-g002.jpg

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本文引用的文献

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External Versus Internal Fixation Techniques for Ankle Arthrodesis: A Systematic Review and Meta-analysis.外固定与内固定技术治疗踝关节融合术:系统评价和荟萃分析。
J Foot Ankle Surg. 2024 Nov-Dec;63(6):769-775. doi: 10.1053/j.jfas.2024.05.010. Epub 2024 Jun 27.
2
Safety of Same-Day Discharge Following Total Ankle Arthroplasty: A Retrospective Cohort Analysis.全踝关节置换术后当日出院的安全性:一项回顾性队列分析。
Foot Ankle Orthop. 2024 Apr 2;9(2):24730114241241300. doi: 10.1177/24730114241241300. eCollection 2024 Apr.
3
Trends in the use of ankle arthrodesis and total ankle replacements in Australia over the past 20 years.
过去20年澳大利亚踝关节融合术和全踝关节置换术的使用趋势。
Eur J Orthop Surg Traumatol. 2024 May;34(4):1997-2001. doi: 10.1007/s00590-024-03884-z. Epub 2024 Mar 19.
4
Contemporary modern total ankle arthroplasty (TAA): A systematic review and meta-analysis of indications, survivorship and complication rates.当代现代全踝关节置换术(TAA):适应证、生存率和并发症发生率的系统评价和荟萃分析。
Surgeon. 2024 Jun;22(3):174-181. doi: 10.1016/j.surge.2024.01.004. Epub 2024 Feb 14.
5
Two-Year Survivorship and Patient-Reported Outcomes of a Prospectively Enrolled Cohort of INFINITY Total Ankle Arthroplasties.前瞻性纳入的INFINITY全踝关节置换术队列的两年生存率及患者报告结局
Foot Ankle Int. 2024 Feb;45(2):150-157. doi: 10.1177/10711007231212484. Epub 2023 Dec 22.
6
Risks of Increased Operative Time and Longer Hospital Stays Based on Age in Total Ankle Arthroplasty.全踝关节置换术中基于年龄的手术时间延长和住院时间延长的风险。
Foot Ankle Spec. 2023 Sep 7:19386400231194775. doi: 10.1177/19386400231194775.
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