Holland John A, Partridge Judith S L, Cronin Antonia J
Department of Transplant Surgery, Renal Medicine, and Urology, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London WC2R 2LS, UK.
J Clin Med. 2025 Apr 29;14(9):3070. doi: 10.3390/jcm14093070.
Demand for renal replacement therapy (including dialysis, transplantation and supportive care) in patients over 60 is increasing. Concerns regarding poorer outcomes and decision-making in this cohort have been raised. Evidence suggests these relate to frailty, multimorbidity and cognitive impairment, all seen frequently in older age. Comprehensive Geriatric Assessment (CGA) is a multidisciplinary methodology proven to improve outcomes relating to this triad and could be transformative for older kidney patients. This national UK survey aims to describe (1) attitudes/beliefs of renal physicians and transplant surgeons in the UK toward the CGA for older potential kidney transplant recipients and those being considered for dialysis or supportive care; (2) provision of CGA services for these patients in the UK; (3) barriers and enablers to the provision of these CGA services in the UK. The UK's 72 renal units (RUs) and 23 adult kidney transplant centres (TCs) were invited to complete online surveys electronically using a protected link (24 April 2024-31 August 2024). The response rate was 100%. Only six RUs offered CGA services. However, respondents overwhelmingly advocated CGA for older patients being considered for transplant (RUs 47/55, TCs 17/19), dialysis (RUs 52/54) and supportive care (RUs 51/54). Lack of funding to support CGA-OS (45/51), lack of available staff to deliver CGA (44/51) and time constraints (36/51) were reported barriers to implementing CGA by RUs. TCs identified lack of funding (13/18) and published evidence (12/18) as the main barriers. : Transplant surgeons and renal physicians alike support CGA for older kidney patients, but only six UK units currently offer the service to these patients. Research developing and implementing CGA for this population is essential to optimise outcomes and influence policy at the national level.
60岁以上患者对肾脏替代疗法(包括透析、移植和支持性护理)的需求正在增加。人们对该人群较差的治疗结果和决策制定提出了担忧。有证据表明,这些问题与虚弱、多种疾病并存和认知障碍有关,这些情况在老年人中很常见。综合老年评估(CGA)是一种多学科方法,已被证明可改善与这三者相关的治疗结果,可能会改变老年肾病患者的治疗情况。这项英国全国性调查旨在描述:(1)英国肾脏内科医生和移植外科医生对老年潜在肾移植受者以及那些正在考虑透析或支持性护理的患者进行综合老年评估的态度/信念;(2)英国为这些患者提供综合老年评估服务的情况;(3)在英国提供这些综合老年评估服务的障碍和促进因素。英国的72个肾脏单位(RUs)和23个成人肾移植中心(TCs)被邀请通过受保护链接以电子方式完成在线调查(2024年4月24日至2024年8月31日)。回复率为100%。只有6个肾脏单位提供综合老年评估服务。然而,受访者压倒性地主张对正在考虑移植的老年患者(肾脏单位47/55,移植中心17/19)、透析患者(肾脏单位52/54)和支持性护理患者(肾脏单位51/54)进行综合老年评估。肾脏单位报告称,缺乏支持综合老年评估的资金(45/51)、缺乏提供综合老年评估的可用工作人员(44/51)和时间限制(36/51)是实施综合老年评估的障碍。移植中心认为缺乏资金(13/18)和已发表的证据(12/18)是主要障碍。移植外科医生和肾脏内科医生都支持对老年肾病患者进行综合老年评估,但目前英国只有6个单位为这些患者提供该服务。开展和实施针对这一人群的综合老年评估研究对于优化治疗结果和影响国家层面的政策至关重要。